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Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity.
Cancer Res. 2007 Aug 1;67(15):7343-9. doi: 10.1158/0008-5472.CAN-07-0107.
Cancer Res. 2007.
PMID: 17671204
Overexpression of Eag1 potassium channels in clinical tumours.
Hemmerlein B, Weseloh RM, Mello de Queiroz F, Knötgen H, Sánchez A, Rubio ME, Martin S, Schliephacke T, Jenke M, Heinz-Joachim-Radzun, Stühmer W, Pardo LA.
Hemmerlein B, et al. Among authors: knotgen h.
Mol Cancer. 2006 Oct 5;5:41. doi: 10.1186/1476-4598-5-41.
Mol Cancer. 2006.
PMID: 17022810
Free PMC article.
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Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.
Downie BR, Sánchez A, Knötgen H, Contreras-Jurado C, Gymnopoulos M, Weber C, Stühmer W, Pardo LA.
Downie BR, et al. Among authors: knotgen h.
J Biol Chem. 2008 Dec 26;283(52):36234-40. doi: 10.1074/jbc.M801830200. Epub 2008 Oct 16.
J Biol Chem. 2008.
PMID: 18927085
Free PMC article.
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