Knighton D - Search Results

1

Avascular and vascular phases of tumour growth in the chick embryo.

Knighton D, Ausprunk D, Tapper D, Folkman J. Knighton D, et al. Br J Cancer. 1977 Mar;35(3):347-56. doi: 10.1038/bjc.1977.49. Br J Cancer. 1977. PMID: 856240 Free PMC article.

2

Vascularization of normal and neoplastic tissues grafted to the chick chorioallantois. Role of host and preexisting graft blood vessels.

Ausprunk DH, Knighton DR, Folkman J. Ausprunk DH, et al. Among authors: knighton dr. Am J Pathol. 1975 Jun;79(3):597-618. Am J Pathol. 1975. PMID: 1094838 Free PMC article.

3

Differentiation of vascular endothelium in the chick chorioallantois: a structural and autoradiographic study.

Ausprunk DH, Knighton DR, Folkman J. Ausprunk DH, et al. Among authors: knighton dr. Dev Biol. 1974 Jun;38(2):237-48. doi: 10.1016/0012-1606(74)90004-9. Dev Biol. 1974. PMID: 4831108 No abstract available.

4

Tumor angiogenesis activity in cells grown in tissue culture.

Klagsbrun M, Knighton D, Folkman J. Klagsbrun M, et al. Among authors: knighton d. Cancer Res. 1976 Jan;36(1):110-4. Cancer Res. 1976. PMID: 1247990

5

A simple procedure for the long-term cultivation of chicken embryos.

Auerbach R, Kubai L, Knighton D, Folkman J. Auerbach R, et al. Among authors: knighton d. Dev Biol. 1974 Dec;41(2):391-4. doi: 10.1016/0012-1606(74)90316-9. Dev Biol. 1974. PMID: 4452416 No abstract available.

6

Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design.

Cheng H, Li C, Bailey S, Baxi SM, Goulet L, Guo L, Hoffman J, Jiang Y, Johnson TO, Johnson TW, Knighton DR, Li J, Liu KK, Liu Z, Marx MA, Walls M, Wells PA, Yin MJ, Zhu J, Zientek M. Cheng H, et al. Among authors: knighton dr. ACS Med Chem Lett. 2012 Nov 7;4(1):91-7. doi: 10.1021/ml300309h. eCollection 2013 Jan 10. ACS Med Chem Lett. 2012. PMID: 24900568 Free PMC article.

7

Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR.

Le PT, Cheng H, Ninkovic S, Plewe M, Huang X, Wang H, Bagrodia S, Sun S, Knighton DR, LaFleur Rogers CM, Pannifer A, Greasley S, Dalvie D, Zhang E. Le PT, et al. Among authors: knighton dr. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5098-103. doi: 10.1016/j.bmcl.2012.05.100. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22749419

8

Discovery of pyrroloaminopyrazoles as novel PAK inhibitors.

Guo C, McAlpine I, Zhang J, Knighton DD, Kephart S, Johnson MC, Li H, Bouzida D, Yang A, Dong L, Marakovits J, Tikhe J, Richardson P, Guo LC, Kania R, Edwards MP, Kraynov E, Christensen J, Piraino J, Lee J, Dagostino E, Del-Carmen C, Deng YL, Smeal T, Murray BW. Guo C, et al. Among authors: knighton dd. J Med Chem. 2012 May 24;55(10):4728-39. doi: 10.1021/jm300204j. Epub 2012 May 14. J Med Chem. 2012. PMID: 22554206

9

Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.

Liu KK, Huang X, Bagrodia S, Chen JH, Greasley S, Cheng H, Sun S, Knighton D, Rodgers C, Rafidi K, Zou A, Xiao J, Yan S. Liu KK, et al. Among authors: knighton d. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1270-4. doi: 10.1016/j.bmcl.2010.12.026. Epub 2010 Dec 10. Bioorg Med Chem Lett. 2011. PMID: 21269826

10

4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.

Liu KK, Bagrodia S, Bailey S, Cheng H, Chen H, Gao L, Greasley S, Hoffman JE, Hu Q, Johnson TO, Knighton D, Liu Z, Marx MA, Nambu MD, Ninkovic S, Pascual B, Rafidi K, Rodgers CM, Smith GL, Sun S, Wang H, Yang A, Yuan J, Zou A. Liu KK, et al. Among authors: knighton d. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6096-9. doi: 10.1016/j.bmcl.2010.08.045. Epub 2010 Aug 14. Bioorg Med Chem Lett. 2010. PMID: 20817449

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