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Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells.
Haselmann V, Kurz A, Bertsch U, Hübner S, Olempska-Müller M, Fritsch J, Häsler R, Pickl A, Fritsche H, Annewanter F, Engler C, Fleig B, Bernt A, Röder C, Schmidt H, Gelhaus C, Hauser C, Egberts JH, Heneweer C, Rohde AM, Böger C, Knippschild U, Röcken C, Adam D, Walczak H, Schütze S, Janssen O, Wulczyn FG, Wajant H, Kalthoff H, Trauzold A. Haselmann V, et al. Among authors: knippschild u. Gastroenterology. 2014 Jan;146(1):278-90. doi: 10.1053/j.gastro.2013.10.009. Epub 2013 Oct 9. Gastroenterology. 2014. PMID: 24120475
Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo.
Brockschmidt C, Hirner H, Huber N, Eismann T, Hillenbrand A, Giamas G, Radunsky B, Ammerpohl O, Bohm B, Henne-Bruns D, Kalthoff H, Leithäuser F, Trauzold A, Knippschild U. Brockschmidt C, et al. Among authors: knippschild u. Gut. 2008 Jun;57(6):799-806. doi: 10.1136/gut.2007.123695. Epub 2008 Jan 18. Gut. 2008. PMID: 18203806
Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.
Hirner H, Günes C, Bischof J, Wolff S, Grothey A, Kühl M, Oswald F, Wegwitz F, Bösl MR, Trauzold A, Henne-Bruns D, Peifer C, Leithäuser F, Deppert W, Knippschild U. Hirner H, et al. Among authors: knippschild u. PLoS One. 2012;7(1):e29709. doi: 10.1371/journal.pone.0029709. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235331 Free PMC article.
CDK9 is a prognostic marker and therapeutic target in pancreatic cancer.
Kretz AL, Schaum M, Richter J, Kitzig EF, Engler CC, Leithäuser F, Henne-Bruns D, Knippschild U, Lemke J. Kretz AL, et al. Among authors: knippschild u. Tumour Biol. 2017 Feb;39(2):1010428317694304. doi: 10.1177/1010428317694304. Tumour Biol. 2017. PMID: 28231737 Free article.
TRAILblazing Strategies for Cancer Treatment.
Kretz AL, Trauzold A, Hillenbrand A, Knippschild U, Henne-Bruns D, von Karstedt S, Lemke J. Kretz AL, et al. Among authors: knippschild u. Cancers (Basel). 2019 Mar 30;11(4):456. doi: 10.3390/cancers11040456. Cancers (Basel). 2019. PMID: 30935038 Free PMC article. Review.
Stress-activated kinases as therapeutic targets in pancreatic cancer.
Traub B, Roth A, Kornmann M, Knippschild U, Bischof J. Traub B, et al. Among authors: knippschild u. World J Gastroenterol. 2021 Aug 14;27(30):4963-4984. doi: 10.3748/wjg.v27.i30.4963. World J Gastroenterol. 2021. PMID: 34497429 Free PMC article. Review.
140 results