Knowles J - Search Results

1

Predictive models for population performance on real biological fitness landscapes.

Rowe W, Wedge DC, Platt M, Kell DB, Knowles J. Rowe W, et al. Among authors: knowles j. Bioinformatics. 2010 Sep 1;26(17):2145-52. doi: 10.1093/bioinformatics/btq353. Epub 2010 Jul 17. Bioinformatics. 2010. PMID: 20639542

2

Computational cluster validation in post-genomic data analysis.

Handl J, Knowles J, Kell DB. Handl J, et al. Among authors: knowles j. Bioinformatics. 2005 Aug 1;21(15):3201-12. doi: 10.1093/bioinformatics/bti517. Epub 2005 May 24. Bioinformatics. 2005. PMID: 15914541 Review.

3

Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape.

Knight CG, Platt M, Rowe W, Wedge DC, Khan F, Day PJ, McShea A, Knowles J, Kell DB. Knight CG, et al. Among authors: knowles j. Nucleic Acids Res. 2009 Jan;37(1):e6. doi: 10.1093/nar/gkn899. Epub 2008 Nov 23. Nucleic Acids Res. 2009. PMID: 19029139 Free PMC article.

4

Analysis of a complete DNA-protein affinity landscape.

Rowe W, Platt M, Wedge DC, Day PJ, Kell DB, Knowles J. Rowe W, et al. Among authors: knowles j. J R Soc Interface. 2010 Mar 6;7(44):397-408. doi: 10.1098/rsif.2009.0193. Epub 2009 Jul 22. J R Soc Interface. 2010. PMID: 19625306 Free PMC article.

5

Multiobjective optimization in bioinformatics and computational biology.

Handl J, Kell DB, Knowles J. Handl J, et al. Among authors: knowles j. IEEE/ACM Trans Comput Biol Bioinform. 2007 Apr-Jun;4(2):279-92. doi: 10.1109/TCBB.2007.070203. IEEE/ACM Trans Comput Biol Bioinform. 2007. PMID: 17473320 Free article. Review.

6

In silico modelling of directed evolution: Implications for experimental design and stepwise evolution.

Wedge DC, Rowe W, Kell DB, Knowles J. Wedge DC, et al. Among authors: knowles j. J Theor Biol. 2009 Mar 7;257(1):131-41. doi: 10.1016/j.jtbi.2008.11.005. Epub 2008 Nov 17. J Theor Biol. 2009. PMID: 19073195

7

Aptamer evolution for array-based diagnostics.

Platt M, Rowe W, Wedge DC, Kell DB, Knowles J, Day PJ. Platt M, et al. Among authors: knowles j. Anal Biochem. 2009 Jul 15;390(2):203-5. doi: 10.1016/j.ab.2009.04.013. Epub 2009 Apr 15. Anal Biochem. 2009. PMID: 19374883

8

Analysis of aptamer sequence activity relationships.

Platt M, Rowe W, Knowles J, Day PJ, Kell DB. Platt M, et al. Among authors: knowles j. Integr Biol (Camb). 2009 Jan;1(1):116-22. doi: 10.1039/b814892a. Epub 2008 Nov 12. Integr Biol (Camb). 2009. PMID: 20023798

9

Exploiting genomic knowledge in optimising molecular breeding programmes: algorithms from evolutionary computing.

O'Hagan S, Knowles J, Kell DB. O'Hagan S, et al. Among authors: knowles j. PLoS One. 2012;7(11):e48862. doi: 10.1371/journal.pone.0048862. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185279 Free PMC article.

10

Insights into the behaviour of systems biology models from dynamic sensitivity and identifiability analysis: a case study of an NF-kappaB signalling pathway.

Yue H, Brown M, Knowles J, Wang H, Broomhead DS, Kell DB. Yue H, et al. Among authors: knowles j. Mol Biosyst. 2006 Dec;2(12):640-9. doi: 10.1039/b609442b. Epub 2006 Oct 23. Mol Biosyst. 2006. PMID: 17216045 Free article.

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