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Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study.
Kolmert J, Gómez C, Balgoma D, Sjödin M, Bood J, Konradsen JR, Ericsson M, Thörngren JO, James A, Mikus M, Sousa AR, Riley JH, Bates S, Bakke PS, Pandis I, Caruso M, Chanez P, Fowler SJ, Geiser T, Howarth P, Horváth I, Krug N, Montuschi P, Sanak M, Behndig A, Shaw DE, Knowles RG, Holweg CTJ, Wheelock ÅM, Dahlén B, Nordlund B, Alving K, Hedlin G, Chung KF, Adcock IM, Sterk PJ, Djukanovic R, Dahlén SE, Wheelock CE; U-BIOPRED Study Group, on behalf of the U-BIOPRED Study Group. Kolmert J, et al. Among authors: knowles rg. Am J Respir Crit Care Med. 2021 Jan 1;203(1):37-53. doi: 10.1164/rccm.201909-1869OC. Am J Respir Crit Care Med. 2021. PMID: 32667261 Free PMC article.
Predictors and associations of the persistent airflow limitation phenotype in asthma: a post-hoc analysis of the ATLANTIS study.
Kole TM, Vanden Berghe E, Kraft M, Vonk JM, Nawijn MC, Siddiqui S, Sun K, Fabbri LM, Rabe KF, Chung KF, Nicolini G, Papi A, Brightling C, Singh D, van der Molen T, Dahlén SE, Agusti A, Faner R, Wedzicha JA, Donaldson GC, Adcock IM, Lahousse L, Kerstjens HAM, van den Berge M; ATLANTIS; U-BIOPRED; CADSET investigators. Kole TM, et al. Lancet Respir Med. 2023 Jan;11(1):55-64. doi: 10.1016/S2213-2600(22)00185-0. Epub 2022 Jul 27. Lancet Respir Med. 2023. PMID: 35907424
The role of nitric oxide in osteoarthritis.
Vuolteenaho K, Moilanen T, Knowles RG, Moilanen E. Vuolteenaho K, et al. Among authors: knowles rg. Scand J Rheumatol. 2007 Jul-Aug;36(4):247-58. doi: 10.1080/03009740701483014. Scand J Rheumatol. 2007. PMID: 17853003 Review.
Asthma similarities across ProAR (Brazil) and U-BIOPRED (Europe) adult cohorts of contrasting locations, ethnicity and socioeconomic status.
Cruz AA, Riley JH, Bansal AT, Ponte EV, Souza-Machado A, Almeida PCA, Biao-Lima V, Davis M, Bates S, Adcock IM, Sterk PJ, Chung KF; ProAR Study Group; U-BIOPRED Study Groups. Cruz AA, et al. Respir Med. 2020 Jan;161:105817. doi: 10.1016/j.rmed.2019.105817. Epub 2019 Nov 26. Respir Med. 2020. PMID: 31790928 Free article.
Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.
Young RJ, Alderton W, Angell AD, Beswick PJ, Brown D, Chambers CL, Crowe MC, Dawson J, Hamlett CC, Hodgson ST, Kleanthous S, Knowles RG, Russell LJ, Stocker R, Woolven JM. Young RJ, et al. Among authors: knowles rg. Bioorg Med Chem Lett. 2011 May 15;21(10):3037-40. doi: 10.1016/j.bmcl.2011.03.038. Epub 2011 Mar 21. Bioorg Med Chem Lett. 2011. PMID: 21482467
Nitric oxide synthases: structure, function and inhibition.
Alderton WK, Cooper CE, Knowles RG. Alderton WK, et al. Among authors: knowles rg. Biochem J. 2001 Aug 1;357(Pt 3):593-615. doi: 10.1042/0264-6021:3570593. Biochem J. 2001. PMID: 11463332 Free PMC article. Review.
121 results