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Mechanism-based inactivation of P450 2A6 by furanocoumarins.
Biochemistry. 1998 Jul 14;37(28):10047-61. doi: 10.1021/bi980003c.
Biochemistry. 1998.
PMID: 9665710
Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
Koenigs LL, Peter RM, Thompson SJ, Rettie AE, Trager WF.
Koenigs LL, et al.
Drug Metab Dispos. 1997 Dec;25(12):1407-15.
Drug Metab Dispos. 1997.
PMID: 9394031
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Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6.
Chen W, Koenigs LL, Thompson SJ, Peter RM, Rettie AE, Trager WF, Nelson SD.
Chen W, et al. Among authors: koenigs ll.
Chem Res Toxicol. 1998 Apr;11(4):295-301. doi: 10.1021/tx9701687.
Chem Res Toxicol. 1998.
PMID: 9548799
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(R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 2A6.
Khojasteh-Bakht SC, Koenigs LL, Peter RM, Trager WF, Nelson SD.
Khojasteh-Bakht SC, et al. Among authors: koenigs ll.
Drug Metab Dispos. 1998 Jul;26(7):701-4.
Drug Metab Dispos. 1998.
PMID: 9660853
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Mechanism-based inactivation of cytochrome P450 2B1 by 8-methoxypsoralen and several other furanocoumarins.
Koenigs LL, Trager WF.
Koenigs LL, et al.
Biochemistry. 1998 Sep 22;37(38):13184-93. doi: 10.1021/bi981198r.
Biochemistry. 1998.
PMID: 9748325
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Electrospray ionization mass spectrometric analysis of intact cytochrome P450: identification of tienilic acid adducts to P450 2C9.
Koenigs LL, Peter RM, Hunter AP, Haining RL, Rettie AE, Friedberg T, Pritchard MP, Shou M, Rushmore TH, Trager WF.
Koenigs LL, et al.
Biochemistry. 1999 Feb 23;38(8):2312-9. doi: 10.1021/bi9823030.
Biochemistry. 1999.
PMID: 10029524
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Metabolism of (R)-(+)-pulegone and (R)-(+)-menthofuran by human liver cytochrome P-450s: evidence for formation of a furan epoxide.
Khojasteh-Bakht SC, Chen W, Koenigs LL, Peter RM, Nelson SD.
Khojasteh-Bakht SC, et al. Among authors: koenigs ll.
Drug Metab Dispos. 1999 May;27(5):574-80.
Drug Metab Dispos. 1999.
PMID: 10220485
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