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The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation.
Dahl JU, Gray MJ, Bazopoulou D, Beaufay F, Lempart J, Koenigsknecht MJ, Wang Y, Baker JR, Hasler WL, Young VB, Sun D, Jakob U. Dahl JU, et al. Among authors: koenigsknecht mj. Nat Microbiol. 2017 Jan 23;2:16267. doi: 10.1038/nmicrobiol.2016.267. Nat Microbiol. 2017. PMID: 28112760 Free PMC article.
NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.
Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. Chen L, et al. Among authors: koenigsknecht mj. Nat Immunol. 2017 May;18(5):541-551. doi: 10.1038/ni.3690. Epub 2017 Mar 13. Nat Immunol. 2017. PMID: 28288099 Free PMC article.
Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract.
Yu A, Baker JR, Fioritto AF, Wang Y, Luo R, Li S, Wen B, Bly M, Tsume Y, Koenigsknecht MJ, Zhang X, Lionberger R, Amidon GL, Hasler WL, Sun D. Yu A, et al. Among authors: koenigsknecht mj. Mol Pharm. 2017 Feb 6;14(2):345-358. doi: 10.1021/acs.molpharmaceut.6b00641. Epub 2016 Dec 23. Mol Pharm. 2017. PMID: 28009518
26 results