Koivunen P - Search Results

1

HER2 regulates cancer stem-like cell phenotype in ALK translocated NSCLC.

Honkanen T, Wilenius E, Koivunen P, Koivunen JP. Honkanen T, et al. Among authors: koivunen jp, koivunen p. Int J Oncol. 2017 Aug;51(2):599-606. doi: 10.3892/ijo.2017.4048. Epub 2017 Jun 21. Int J Oncol. 2017. PMID: 28656214

2

A novel treatment strategy for EGFR mutant NSCLC with T790M-mediated acquired resistance.

Taube E, Jokinen E, Koivunen P, Koivunen JP. Taube E, et al. Among authors: koivunen jp, koivunen p. Int J Cancer. 2012 Aug 15;131(4):970-9. doi: 10.1002/ijc.26461. Epub 2011 Nov 8. Int J Cancer. 2012. PMID: 21953013 Free article.

3

Combining targeted drugs to overcome and prevent resistance of solid cancers with some stem-like cell features.

Jokinen E, Laurila N, Koivunen P, Koivunen JP. Jokinen E, et al. Among authors: koivunen jp, koivunen p. Oncotarget. 2014 Oct 15;5(19):9295-307. doi: 10.18632/oncotarget.2424. Oncotarget. 2014. PMID: 25238228 Free PMC article.

4

Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases.

Laukka T, Myllykoski M, Looper RE, Koivunen P. Laukka T, et al. Among authors: koivunen p. J Mol Biol. 2018 Sep 14;430(18 Pt B):3081-3092. doi: 10.1016/j.jmb.2018.06.048. Epub 2018 Jul 5. J Mol Biol. 2018. PMID: 29981745

5

Expression and Roles of Individual HIF Prolyl 4-Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium.

Dengler F, Sova S, Salo AM, Mäki JM, Koivunen P, Myllyharju J. Dengler F, et al. Among authors: koivunen p. Int J Mol Sci. 2021 Apr 14;22(8):4038. doi: 10.3390/ijms22084038. Int J Mol Sci. 2021. PMID: 33919829 Free PMC article.

6

HIF-1α is upregulated in human mesenchymal stem cells.

Palomäki S, Pietilä M, Laitinen S, Pesälä J, Sormunen R, Lehenkari P, Koivunen P. Palomäki S, et al. Among authors: koivunen p. Stem Cells. 2013 Sep;31(9):1902-9. doi: 10.1002/stem.1435. Stem Cells. 2013. PMID: 23744828

7

Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection.

Kerkelä R, Karsikas S, Szabo Z, Serpi R, Magga J, Gao E, Alitalo K, Anisimov A, Sormunen R, Pietilä I, Vainio L, Koch WJ, Kivirikko KI, Myllyharju J, Koivunen P. Kerkelä R, et al. Among authors: koivunen p. Mol Cell Biol. 2013 Aug;33(16):3321-9. doi: 10.1128/MCB.00432-13. Epub 2013 Jun 17. Mol Cell Biol. 2013. PMID: 23775121 Free PMC article.

8

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.

Laukka T, Mariani CJ, Ihantola T, Cao JZ, Hokkanen J, Kaelin WG Jr, Godley LA, Koivunen P. Laukka T, et al. Among authors: koivunen p. J Biol Chem. 2016 Feb 19;291(8):4256-65. doi: 10.1074/jbc.M115.688762. Epub 2015 Dec 23. J Biol Chem. 2016. PMID: 26703470 Free PMC article.

9

CD146(+) cells are essential for kidney vasculature development.

Halt KJ, Pärssinen HE, Junttila SM, Saarela U, Sims-Lucas S, Koivunen P, Myllyharju J, Quaggin S, Skovorodkin IN, Vainio SJ. Halt KJ, et al. Among authors: koivunen p. Kidney Int. 2016 Aug;90(2):311-324. doi: 10.1016/j.kint.2016.02.021. Epub 2016 Apr 18. Kidney Int. 2016. PMID: 27165833 Free article.

10

USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner.

Richter K, Paakkola T, Mennerich D, Kubaichuk K, Konzack A, Ali-Kippari H, Kozlova N, Koivunen P, Haapasaari KM, Jukkola-Vuorinen A, Teppo HR, Dimova EY, Bloigu R, Szabo Z, Kerkelä R, Kietzmann T. Richter K, et al. Among authors: koivunen p. Mol Cancer Res. 2018 Jun;16(6):1000-1012. doi: 10.1158/1541-7786.MCR-17-0452. Epub 2018 Mar 15. Mol Cancer Res. 2018. PMID: 29545478

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