Kolars JC - Search Results

1

First-pass metabolism of cyclosporin by the gut.

Kolars JC, Awni WM, Merion RM, Watkins PB. Kolars JC, et al. Lancet. 1991 Dec 14;338(8781):1488-90. doi: 10.1016/0140-6736(91)92302-i. Lancet. 1991. PMID: 1683920 Free article.

2

CYP3A gene expression in human gut epithelium.

Kolars JC, Lown KS, Schmiedlin-Ren P, Ghosh M, Fang C, Wrighton SA, Merion RM, Watkins PB. Kolars JC, et al. Pharmacogenetics. 1994 Oct;4(5):247-59. doi: 10.1097/00008571-199410000-00003. Pharmacogenetics. 1994. PMID: 7894497

3

Cyclosporine metabolism by P450IIIA in rat enterocytes--another determinant of oral bioavailability?

Kolars JC, Stetson PL, Rush BD, Ruwart MJ, Schmiedlin-Ren P, Duell EA, Voorhees JJ, Watkins PB. Kolars JC, et al. Transplantation. 1992 Mar;53(3):596-602. doi: 10.1097/00007890-199203000-00021. Transplantation. 1992. PMID: 1549853

4

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA.

Lucey MR, Kolars JC, Merion RM, Campbell DA, Aldrich M, Watkins PB. Lucey MR, et al. Among authors: kolars jc. Lancet. 1990 Jan 6;335(8680):11-5. doi: 10.1016/0140-6736(90)90137-t. Lancet. 1990. PMID: 1967328 Free article.

5

The erythromycin breath test selectively measures P450IIIA in patients with severe liver disease.

Lown K, Kolars J, Turgeon K, Merion R, Wrighton SA, Watkins PB. Lown K, et al. Clin Pharmacol Ther. 1992 Mar;51(3):229-38. doi: 10.1038/clpt.1992.17. Clin Pharmacol Ther. 1992. PMID: 1544283 Free article.

6

Omeprazole and aryl hydrocarbon hydroxylases: should we be worried?

Kolars JC, Turgeon DK, Watkins PB. Kolars JC, et al. Hepatology. 1991 Jan;13(1):197-9. doi: 10.1002/hep.1840130131. Hepatology. 1991. PMID: 1988343 Free article. No abstract available.

7

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, Wrighton SA, Watkins PB. Lown KS, et al. Among authors: kolars jc. Drug Metab Dispos. 1994 Nov-Dec;22(6):947-55. Drug Metab Dispos. 1994. PMID: 7895614

8

Aflatoxin B1-adduct formation in rat and human small bowel enterocytes.

Kolars JC, Benedict P, Schmiedlin-Ren P, Watkins PB. Kolars JC, et al. Gastroenterology. 1994 Feb;106(2):433-9. doi: 10.1016/0016-5085(94)90602-5. Gastroenterology. 1994. PMID: 8299909

9

Cultured adult rat jejunal explants as a model for studying regulation of CYP3A.

Schmiedlin-Ren P, Benedict PE, Dobbins WO 3rd, Ghosh M, Kolars JC, Watkins PB. Schmiedlin-Ren P, et al. Among authors: kolars jc. Biochem Pharmacol. 1993 Sep 1;46(5):905-18. doi: 10.1016/0006-2952(93)90501-m. Biochem Pharmacol. 1993. PMID: 8373442 Free article.

10

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes.

Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Kolars JC, et al. J Clin Invest. 1992 Nov;90(5):1871-8. doi: 10.1172/JCI116064. J Clin Invest. 1992. PMID: 1430211 Free PMC article.

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