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Engineering of CRISPR-Cas12b for human genome editing.
Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F. Strecker J, et al. Among authors: koopal b. Nat Commun. 2019 Jan 22;10(1):212. doi: 10.1038/s41467-018-08224-4. Nat Commun. 2019. PMID: 30670702 Free PMC article.
A long look at short prokaryotic Argonautes.
Koopal B, Mutte SK, Swarts DC. Koopal B, et al. Trends Cell Biol. 2023 Jul;33(7):605-618. doi: 10.1016/j.tcb.2022.10.005. Epub 2022 Nov 22. Trends Cell Biol. 2023. PMID: 36428175 Review.
The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function.
Proietti Onori M, Koopal B, Everman DB, Worthington JD, Jones JR, Ploeg MA, Mientjes E, van Bon BW, Kleefstra T, Schulman H, Kushner SA, Küry S, Elgersma Y, van Woerden GM. Proietti Onori M, et al. Among authors: koopal b. Hum Mutat. 2018 Dec;39(12):2008-2024. doi: 10.1002/humu.23647. Epub 2018 Sep 19. Hum Mutat. 2018. PMID: 30184290 Free PMC article.