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Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.
Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Pappo O, Schweitzer N, Tornillo L, Kanarek N, Quagliata L, Zreik F, Porat RM, Finkelstein R, Reuter H, Koschny R, Ganten T, Mogler C, Shibolet O, Hess J, Breuhahn K, Grunewald M, Schirmacher P, Vogel A, Terracciano L, Angel P, Ben-Neriah Y, Pikarsky E. Horwitz E, et al. Among authors: koschny r. Cancer Discov. 2014 Jun;4(6):730-43. doi: 10.1158/2159-8290.CD-13-0782. Epub 2014 Mar 31. Cancer Discov. 2014. PMID: 24687604
Molecular characterization of hepatic epithelioid hemangioendothelioma reveals alterations in various genes involved in DNA repair, epigenetic regulation, signaling pathways, and cell cycle control.
Mogler C, Koschny R, Heilig CE, Frohling S, Schirmacher P, Weichert W, Pfarr N. Mogler C, et al. Among authors: koschny r. Genes Chromosomes Cancer. 2020 Feb;59(2):106-110. doi: 10.1002/gcc.22795. Epub 2019 Sep 3. Genes Chromosomes Cancer. 2020. PMID: 31390105
71 results