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Novel regulation of MHC class II function in B cells.
Matsuki Y, Ohmura-Hoshino M, Goto E, Aoki M, Mito-Yoshida M, Uematsu M, Hasegawa T, Koseki H, Ohara O, Nakayama M, Toyooka K, Matsuoka K, Hotta H, Yamamoto A, Ishido S. Matsuki Y, et al. Among authors: koseki h. EMBO J. 2007 Feb 7;26(3):846-54. doi: 10.1038/sj.emboj.7601556. Epub 2007 Jan 25. EMBO J. 2007. PMID: 17255932 Free PMC article.
KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands.
Farcas AM, Blackledge NP, Sudbery I, Long HK, McGouran JF, Rose NR, Lee S, Sims D, Cerase A, Sheahan TW, Koseki H, Brockdorff N, Ponting CP, Kessler BM, Klose RJ. Farcas AM, et al. Among authors: koseki h. Elife. 2012 Dec 18;1:e00205. doi: 10.7554/eLife.00205. Elife. 2012. PMID: 23256043 Free PMC article.
Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing.
Miyazaki H, Higashimoto K, Yada Y, Endo TA, Sharif J, Komori T, Matsuda M, Koseki Y, Nakayama M, Soejima H, Handa H, Koseki H, Hirose S, Nishioka K. Miyazaki H, et al. Among authors: koseki h, koseki y. PLoS Genet. 2013 Nov;9(11):e1003897. doi: 10.1371/journal.pgen.1003897. Epub 2013 Nov 7. PLoS Genet. 2013. PMID: 24244179 Free PMC article.
The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.
Obata Y, Furusawa Y, Endo TA, Sharif J, Takahashi D, Atarashi K, Nakayama M, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi T, Tajima S, Masumoto H, Ohara O, Honda K, Hori S, Ohno H, Koseki H, Hase K. Obata Y, et al. Among authors: koseki h. Nat Immunol. 2014 Jun;15(6):571-9. doi: 10.1038/ni.2886. Epub 2014 Apr 28. Nat Immunol. 2014. PMID: 24777532
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.
Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LLP, Ito S, Cooper S, Kondo K, Koseki Y, Ishikura T, Long HK, Sheahan TW, Brockdorff N, Kessler BM, Koseki H, Klose RJ. Blackledge NP, et al. Among authors: koseki h, koseki y. Cell. 2014 Jun 5;157(6):1445-1459. doi: 10.1016/j.cell.2014.05.004. Epub 2014 May 22. Cell. 2014. PMID: 24856970 Free PMC article.
551 results