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Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α1-adrenergic receptor antagonist with uro-selective activity.
Rak A, Canale V, Marciniec K, Żmudzki P, Kotańska M, Knutelska J, Siwek A, Stachowicz G, Bednarski M, Nowiński L, Zygmunt M, Zajdel P, Sapa J. Rak A, et al. Among authors: kotanska m. Bioorg Med Chem. 2016 Nov 1;24(21):5582-5591. doi: 10.1016/j.bmc.2016.09.017. Epub 2016 Sep 10. Bioorg Med Chem. 2016. PMID: 27658792
Chemically Homogenous Compounds with Antagonistic Properties at All α1-Adrenoceptor Subtypes but not β1-Adrenoceptor Attenuate Adrenaline-Induced Arrhythmia in Rats.
Pytka K, Lustyk K, Żmudzka E, Kotańska M, Siwek A, Zygmunt M, Dziedziczak A, Śniecikowska J, Olczyk A, Gałuszka A, Śmieja J, Waszkielewicz AM, Marona H, Filipek B, Sapa J, Mogilski S. Pytka K, et al. Among authors: kotanska m. Front Pharmacol. 2016 Aug 3;7:229. doi: 10.3389/fphar.2016.00229. eCollection 2016. Front Pharmacol. 2016. PMID: 27536240 Free PMC article.
Anti-aggregation effect of aroxyalkyl derivatives of 2-methoxyphenylpiperazine is due to their 5-HT2A and α2-adrenoceptor antagonistic properties. A comparison with ketanserin, sarpogrelate, prazosin, yohimbine and ARC239.
Kubacka M, Kazek G, Kotańska M, Filipek B, Waszkielewicz AM, Mogilski S. Kubacka M, et al. Among authors: kotanska m. Eur J Pharmacol. 2018 Jan 5;818:263-270. doi: 10.1016/j.ejphar.2017.10.053. Epub 2017 Oct 27. Eur J Pharmacol. 2018. PMID: 29111111
Synthesis and biological evaluation of N-arylpiperazine derivatives of 4,4-dimethylisoquinoline-1,3(2H,4H)-dione as potential antiplatelet agents.
Marcinkowska M, Kotańska M, Zagórska A, Śniecikowska J, Kubacka M, Siwek A, Bucki A, Pawłowski M, Bednarski M, Sapa J, Starek M, Dąbrowska M, Kołaczkowski M. Marcinkowska M, et al. Among authors: kotanska m. J Enzyme Inhib Med Chem. 2018 Dec;33(1):536-545. doi: 10.1080/14756366.2018.1437155. J Enzyme Inhib Med Chem. 2018. PMID: 29482394 Free PMC article.
Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands.
Szczepańska K, Karcz T, Mogilski S, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S, Lubelska A, Olejarz A, Kotańska M, Sadek B, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: kotanska m. Eur J Med Chem. 2018 May 25;152:223-234. doi: 10.1016/j.ejmech.2018.04.043. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29723785
Synthesis and Pharmacological Evaluation of Novel Silodosin-Based Arylsulfonamide Derivatives as α1A/α1D-Adrenergic Receptor Antagonist with Potential Uroselective Profile.
Canale V, Rak A, Kotańska M, Knutelska J, Siwek A, Bednarski M, Nowiński L, Zygmunt M, Koczurkiewicz P, Pękala E, Sapa J, Zajdel P. Canale V, et al. Among authors: kotanska m. Molecules. 2018 Aug 29;23(9):2175. doi: 10.3390/molecules23092175. Molecules. 2018. PMID: 30158432 Free PMC article.
61 results