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MSUT2 is a determinant of susceptibility to tau neurotoxicity.
Guthrie CR, Greenup L, Leverenz JB, Kraemer BC. Guthrie CR, et al. Among authors: kraemer bc. Hum Mol Genet. 2011 May 15;20(10):1989-99. doi: 10.1093/hmg/ddr079. Epub 2011 Feb 25. Hum Mol Genet. 2011. PMID: 21355046 Free PMC article.
Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation.
Watkins GR, Wang N, Mazalouskas MD, Gomez RJ, Guthrie CR, Kraemer BC, Schweiger S, Spiller BW, Wadzinski BE. Watkins GR, et al. Among authors: kraemer bc. J Biol Chem. 2012 Jul 13;287(29):24207-15. doi: 10.1074/jbc.M112.368613. Epub 2012 May 21. J Biol Chem. 2012. PMID: 22613722 Free PMC article.
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