Krippner G - Search Results

1

Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists.

Deora GS, Qin CX, Vecchio EA, Debono AJ, Priebbenow DL, Brady RM, Beveridge J, Teguh SC, Deo M, May LT, Krippner G, Ritchie RH, Baell JB. Deora GS, et al. Among authors: krippner g. J Med Chem. 2019 May 23;62(10):5242-5248. doi: 10.1021/acs.jmedchem.8b01912. Epub 2019 May 13. J Med Chem. 2019. PMID: 31038950

2

An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus.

Watson KG, Brown RN, Cameron R, Chalmers DK, Hamilton S, Jin B, Krippner GY, Luttick A, McConnell DB, Reece PA, Ryan J, Stanislawski PC, Tucker SP, Wu WY, Barnard DL, Sidwell RW. Watson KG, et al. Among authors: krippner gy. J Med Chem. 2003 Jul 17;46(15):3181-4. doi: 10.1021/jm0202876. J Med Chem. 2003. PMID: 12852746

3

Synthesis of a polymeric 4-N-linked sialoside which inhibits influenza virus hemagglutinin.

Wu WY, Jin B, Krippner GY, Watson KG. Wu WY, et al. Among authors: krippner gy. Bioorg Med Chem Lett. 2000 Feb 21;10(4):341-3. doi: 10.1016/s0960-894x(00)00007-x. Bioorg Med Chem Lett. 2000. PMID: 10714495

4

Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase.

Watson KG, Cameron R, Fenton RJ, Gower D, Hamilton S, Jin B, Krippner GY, Luttick A, McConnell D, MacDonald SJ, Mason AM, Nguyen V, Tucker SP, Wu WY. Watson KG, et al. Among authors: krippner gy. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1589-92. doi: 10.1016/j.bmcl.2003.09.102. Bioorg Med Chem Lett. 2004. PMID: 15006410

5

Improving the membrane permeability of sialic acid derivatives.

Altamore TM, Duggan PJ, Krippner GY. Altamore TM, et al. Bioorg Med Chem. 2006 Feb 15;14(4):1126-33. doi: 10.1016/j.bmc.2005.09.028. Epub 2005 Oct 7. Bioorg Med Chem. 2006. PMID: 16214357

6

2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder.

Brown RN, Cameron R, Chalmers DK, Hamilton S, Luttick A, Krippner GY, McConnell DB, Nearn R, Stanislawski PC, Tucker SP, Watson KG. Brown RN, et al. Among authors: krippner gy. Bioorg Med Chem Lett. 2005 Apr 15;15(8):2051-5. doi: 10.1016/j.bmcl.2005.02.054. Bioorg Med Chem Lett. 2005. PMID: 15808466

7

An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus.

Feil SC, Hamilton S, Krippner GY, Lin B, Luttick A, McConnell DB, Nearn R, Parker MW, Ryan J, Stanislawski PC, Tucker SP, Watson KG, Morton CJ. Feil SC, et al. Among authors: krippner gy. ACS Med Chem Lett. 2012 Feb 13;3(4):303-7. doi: 10.1021/ml2002955. eCollection 2012 Apr 12. ACS Med Chem Lett. 2012. PMID: 24900468 Free PMC article.

8

GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors.

Hu H, Armstrong PC, Khalil E, Chen YC, Straub A, Li M, Soosairajah J, Hagemeyer CE, Bassler N, Huang D, Ahrens I, Krippner G, Gardiner E, Peter K. Hu H, et al. Among authors: krippner g. PLoS One. 2011 Apr 28;6(4):e19190. doi: 10.1371/journal.pone.0019190. PLoS One. 2011. PMID: 21552524 Free PMC article.

9

Transitional changes in the structure of C-reactive protein create highly pro-inflammatory molecules: Therapeutic implications for cardiovascular diseases.

Zeller J, Bogner B, McFadyen JD, Kiefer J, Braig D, Pietersz G, Krippner G, Nero TL, Morton CJ, Shing KSCT, Parker MW, Peter K, Eisenhardt SU. Zeller J, et al. Among authors: krippner g. Pharmacol Ther. 2022 Jul;235:108165. doi: 10.1016/j.pharmthera.2022.108165. Epub 2022 Mar 3. Pharmacol Ther. 2022. PMID: 35247517 Review.

10

Treatment of type 2 diabetes with the designer cytokine IC7Fc.

Findeisen M, Allen TL, Henstridge DC, Kammoun H, Brandon AE, Baggio LL, Watt KI, Pal M, Cron L, Estevez E, Yang C, Kowalski GM, O'Reilly L, Egan C, Sun E, Thai LM, Krippner G, Adams TE, Lee RS, Grötzinger J, Garbers C, Risis S, Kraakman MJ, Mellet NA, Sligar J, Kimber ET, Young RL, Cowley MA, Bruce CR, Meikle PJ, Baldock PA, Gregorevic P, Biden TJ, Cooney GJ, Keating DJ, Drucker DJ, Rose-John S, Febbraio MA. Findeisen M, et al. Among authors: krippner g. Nature. 2019 Oct;574(7776):63-68. doi: 10.1038/s41586-019-1601-9. Epub 2019 Sep 25. Nature. 2019. PMID: 31554967

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