Kristensen KK - Search Results

1

Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase.

Kumari A, Grønnemose AL, Kristensen KK, Winther AL, Young SG, Jørgensen TJD, Ploug M. Kumari A, et al. Among authors: kristensen kk. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2221888120. doi: 10.1073/pnas.2221888120. Epub 2023 Apr 24. Proc Natl Acad Sci U S A. 2023. PMID: 37094117 Free PMC article.

2

The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain.

Mysling S, Kristensen KK, Larsson M, Beigneux AP, Gårdsvoll H, Fong LG, Bensadouen A, Jørgensen TJ, Young SG, Ploug M. Mysling S, et al. Among authors: kristensen kk. Elife. 2016 Jan 3;5:e12095. doi: 10.7554/eLife.12095. Elife. 2016. PMID: 26725083 Free PMC article.

3

The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding.

Mysling S, Kristensen KK, Larsson M, Kovrov O, Bensadouen A, Jørgensen TJ, Olivecrona G, Young SG, Ploug M. Mysling S, et al. Among authors: kristensen kk. Elife. 2016 Dec 8;5:e20958. doi: 10.7554/eLife.20958. Elife. 2016. PMID: 27929370 Free PMC article.

4

A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase.

Kristensen KK, Midtgaard SR, Mysling S, Kovrov O, Hansen LB, Skar-Gislinge N, Beigneux AP, Kragelund BB, Olivecrona G, Young SG, Jørgensen TJD, Fong LG, Ploug M. Kristensen KK, et al. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E6020-E6029. doi: 10.1073/pnas.1806774115. Epub 2018 Jun 13. Proc Natl Acad Sci U S A. 2018. PMID: 29899144 Free PMC article.

5

Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.

Birrane G, Beigneux AP, Dwyer B, Strack-Logue B, Kristensen KK, Francone OL, Fong LG, Mertens HDT, Pan CQ, Ploug M, Young SG, Meiyappan M. Birrane G, et al. Among authors: kristensen kk. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1723-1732. doi: 10.1073/pnas.1817984116. Epub 2018 Dec 17. Proc Natl Acad Sci U S A. 2019. PMID: 30559189 Free PMC article.

6

On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity.

Kovrov O, Kristensen KK, Larsson E, Ploug M, Olivecrona G. Kovrov O, et al. Among authors: kristensen kk. J Lipid Res. 2019 Apr;60(4):783-793. doi: 10.1194/jlr.M088807. Epub 2019 Jan 27. J Lipid Res. 2019. PMID: 30686789 Free PMC article.

7

Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism.

Kristensen KK, Leth-Espensen KZ, Mertens HDT, Birrane G, Meiyappan M, Olivecrona G, Jørgensen TJD, Young SG, Ploug M. Kristensen KK, et al. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4337-4346. doi: 10.1073/pnas.1920202117. Epub 2020 Feb 7. Proc Natl Acad Sci U S A. 2020. PMID: 32034094 Free PMC article.

8

ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL's hydrolase domain.

Kristensen KK, Leth-Espensen KZ, Young SG, Ploug M. Kristensen KK, et al. J Lipid Res. 2020 Sep;61(9):1253. doi: 10.1194/jlr.ILR120000780. Epub 2020 Apr 23. J Lipid Res. 2020. PMID: 32327484 Free PMC article. No abstract available.

9

The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding.

Leth-Espensen KZ, Kristensen KK, Kumari A, Winther AL, Young SG, Jørgensen TJD, Ploug M. Leth-Espensen KZ, et al. Among authors: kristensen kk. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2026650118. doi: 10.1073/pnas.2026650118. Proc Natl Acad Sci U S A. 2021. PMID: 33723082 Free PMC article.

10

The Importance of Lipoprotein Lipase Regulation in Atherosclerosis.

Kumari A, Kristensen KK, Ploug M, Winther AL. Kumari A, et al. Among authors: kristensen kk. Biomedicines. 2021 Jul 6;9(7):782. doi: 10.3390/biomedicines9070782. Biomedicines. 2021. PMID: 34356847 Free PMC article. Review.

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