Kristian P - Search Results

1

Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease.

Hamulakova S, Janovec L, Hrabinova M, Kristian P, Kuca K, Banasova M, Imrich J. Hamulakova S, et al. Among authors: kristian p. Eur J Med Chem. 2012 Sep;55:23-31. doi: 10.1016/j.ejmech.2012.06.051. Epub 2012 Jul 4. Eur J Med Chem. 2012. PMID: 22818849

2

3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents.

Plsikova J, Janovec L, Koval J, Ungvarsky J, Mikes J, Jendzelovsky R, Fedorocko P, Imrich J, Kristian P, Kasparkova J, Brabec V, Kozurkova M. Plsikova J, et al. Among authors: kristian p. Eur J Med Chem. 2012 Nov;57:283-95. doi: 10.1016/j.ejmech.2012.09.020. Epub 2012 Sep 23. Eur J Med Chem. 2012. PMID: 23072739

3

Novel tacrine/acridine anticholinesterase inhibitors with piperazine and thiourea linkers.

Hamulakova S, Imrich J, Janovec L, Kristian P, Danihel I, Holas O, Pohanka M, Böhm S, Kozurkova M, Kuca K. Hamulakova S, et al. Among authors: kristian p. Int J Biol Macromol. 2014 Sep;70:435-9. doi: 10.1016/j.ijbiomac.2014.06.064. Epub 2014 Jul 15. Int J Biol Macromol. 2014. PMID: 25036600

4

Synthesis and biological evaluation of novel tacrine derivatives and tacrine-coumarin hybrids as cholinesterase inhibitors.

Hamulakova S, Janovec L, Hrabinova M, Spilovska K, Korabecny J, Kristian P, Kuca K, Imrich J. Hamulakova S, et al. Among authors: kristian p. J Med Chem. 2014 Aug 28;57(16):7073-84. doi: 10.1021/jm5008648. Epub 2014 Aug 12. J Med Chem. 2014. PMID: 25089370

5

Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules.

Hamulakova S, Poprac P, Jomova K, Brezova V, Lauro P, Drostinova L, Jun D, Sepsova V, Hrabinova M, Soukup O, Kristian P, Gazova Z, Bednarikova Z, Kuca K, Valko M. Hamulakova S, et al. Among authors: kristian p. J Inorg Biochem. 2016 Aug;161:52-62. doi: 10.1016/j.jinorgbio.2016.05.001. Epub 2016 May 5. J Inorg Biochem. 2016. PMID: 27230386

6

Synthesis, DNA interaction, and cytotoxic activity of a novel proflavine-dithiazolidinone pharmacophore.

Janovec L, Sabolova D, Kozurkova M, Paulíkova H, Kristian P, Ungvarský J, Moravcíkova E, Bajdichova M, Podhradský D, Imrich J. Janovec L, et al. Among authors: kristian p. Bioconjug Chem. 2007 Jan-Feb;18(1):93-100. doi: 10.1021/bc060168v. Bioconjug Chem. 2007. PMID: 17226961

7

Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1',1''-(acridin-3,6-diyl)-3',3''-dialkyldiureas.

Kozurková M, Sabolová D, Janovec L, Mikes J, Koval' J, Ungvarský J, Stefanisinová M, Fedorocko P, Kristian P, Imrich J. Kozurková M, et al. Among authors: kristian p. Bioorg Med Chem. 2008 Apr 1;16(7):3976-84. doi: 10.1016/j.bmc.2008.01.026. Epub 2008 Jan 19. Bioorg Med Chem. 2008. PMID: 18258438

8

DNA binding acridine-thiazolidinone agents affecting intracellular glutathione.

Paulíková H, Vantová Z, Hunáková L, Čižeková L, Čarná M, Kožurková M, Sabolová D, Kristian P, Hamul'aková S, Imrich J. Paulíková H, et al. Among authors: kristian p. Bioorg Med Chem. 2012 Dec 15;20(24):7139-48. doi: 10.1016/j.bmc.2012.09.068. Epub 2012 Oct 12. Bioorg Med Chem. 2012. PMID: 23122936

9

Novel trisubstituted acridines as human telomeric quadruplex binding ligands.

Ungvarsky J, Plsikova J, Janovec L, Koval J, Mikes J, Mikesová L, Harvanova D, Fedorocko P, Kristian P, Kasparkova J, Brabec V, Vojtickova M, Sabolova D, Stramova Z, Rosocha J, Imrich J, Kozurkova M. Ungvarsky J, et al. Among authors: kristian p. Bioorg Chem. 2014 Dec;57:13-29. doi: 10.1016/j.bioorg.2014.07.010. Epub 2014 Aug 10. Bioorg Chem. 2014. PMID: 25171773

10

DNA binding properties and evaluation of cytotoxic activity of 9,10-bis-N-substituted (aminomethyl)anthracenes.

Kozurková M, Sabolová D, Paulíková H, Janovec L, Kristian P, Bajdichová M, Busa J, Podhradský D, Imrich J. Kozurková M, et al. Among authors: kristian p. Int J Biol Macromol. 2007 Oct 1;41(4):415-22. doi: 10.1016/j.ijbiomac.2007.05.013. Epub 2007 Jun 17. Int J Biol Macromol. 2007. PMID: 17659335

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