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Page 1
Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial.
Heinrich MC, Jones RL, George S, Gelderblom H, Schöffski P, von Mehren M, Zalcberg JR, Kang YK, Razak AA, Trent J, Attia S, Le Cesne A, Siontis BL, Goldstein D, Boye K, Sanchez C, Steeghs N, Rutkowski P, Druta M, Serrano C, Somaiah N, Chi P, Reichmann W, Sprott K, Achour H, Sherman ML, Ruiz-Soto R, Blay JY, Bauer S. Heinrich MC, et al. Nat Med. 2024 Feb;30(2):498-506. doi: 10.1038/s41591-023-02734-5. Epub 2024 Jan 5. Nat Med. 2024. PMID: 38182785 Free PMC article. Clinical Trial.
Quantum Chemical Analysis of Molecular and Fragment Ions Produced by Field Ionization of Methyl Stearate.
Takayama M, Ubukata M, Nagatomo K, Tamura J, Kubota A. Takayama M, et al. J Am Soc Mass Spectrom. 2023 Dec 6;34(12):2731-2738. doi: 10.1021/jasms.3c00277. Epub 2023 Oct 30. J Am Soc Mass Spectrom. 2023. PMID: 37902792
The TDDFT calculations suggest that methyl stearate is ionized via two processes, namely a 7.43 eV excitation and a tunneling effect, while the high electric field of 10(10) V/m enables analyte molecules to ionize at an effective 6 eV lower than the 9.26 eV ionization ener …
The TDDFT calculations suggest that methyl stearate is ionized via two processes, namely a 7.43 eV excitation and a tunneling effect, while …
Effect of Alkyl Chain Length on Charge Transport Property of Anthracene-Based Organic Semiconductors.
Zhang D, Yokomori S, Kameyama R, Zhao C, Ueda A, Zhang L, Kumai R, Murakami Y, Meng H, Mori H. Zhang D, et al. ACS Appl Mater Interfaces. 2021 Jan 13;13(1):989-998. doi: 10.1021/acsami.0c16144. Epub 2020 Dec 17. ACS Appl Mater Interfaces. 2021. PMID: 33332081
Our newly synthesized C(1)-, C(3)-, and C(4)-Ph-Ants show hole mobilities of up to 2.40, 1.34, and 1.00 cm(2) V(-1) s(-1), respectively, with mobilities of 3.40, 1.57, and 0.82 cm(2) V(-1) s(-1) for C(0)-, C(2)-, and C(6)-Ph-Ants, indicating an increasing tendency o …
Our newly synthesized C(1)-, C(3)-, and C(4)-Ph-Ants show hole mobilities of up to 2.40, 1.34, and 1.00 cm(2) V(-1) s(-1), respective …
Enantiomeric determination of α-lipoic acid in urine by LC/MS/MS.
Kobayashi Y, Ito R, Saito K. Kobayashi Y, et al. J Pharm Biomed Anal. 2019 Mar 20;166:435-439. doi: 10.1016/j.jpba.2019.01.042. Epub 2019 Jan 28. J Pharm Biomed Anal. 2019. PMID: 30731341
In the LC/MS/MS method, CHIRALPAK AD-3R was used as the chiral separation column and acetonitrile-methanol-formic acid (10 mM) (25:25:50, v/v/v) was used as the mobile phase. (13)C(4) 1,2,5,6-d-l-alpha-Lipoic acid was used as the internal standard. ...
In the LC/MS/MS method, CHIRALPAK AD-3R was used as the chiral separation column and acetonitrile-methanol-formic acid (10 mM) (25:25:50, …
The hydrocarbon-bearing clathrasil chibaite and its host-guest structure at low temperature.
Scheidl KS, Effenberger HS, Yagi T, Momma K, Miletich R. Scheidl KS, et al. IUCrJ. 2018 Aug 8;5(Pt 5):595-607. doi: 10.1107/S2052252518009107. eCollection 2018 Sep 1. IUCrJ. 2018. PMID: 30224963 Free PMC article.
The O atoms of the structure at room temperature, which globally conforms to space group [V = 7348.9 (17) A(3), a = 19.4420 (15) A], have anomalous anisotropic displacement parameters indicating a static or dynamic disorder. ...A monoclinic twinned superstructure was deriv …
The O atoms of the structure at room temperature, which globally conforms to space group [V = 7348.9 (17) A(3), a = 19.4420 (15) A], …
Total Synthesis of Resiniferatoxin Enabled by Radical-Mediated Three-Component Coupling and 7-endo Cyclization.
Hashimoto S, Katoh SI, Kato T, Urabe D, Inoue M. Hashimoto S, et al. J Am Chem Soc. 2017 Nov 15;139(45):16420-16429. doi: 10.1021/jacs.7b10177. Epub 2017 Oct 31. J Am Chem Soc. 2017. PMID: 29041773
The 6-membered 17b, prepared from d-ribose derivative 19, was designed to possess the caged orthoester structure with alpha-alkoxy selenide as a radical precursor. Upon treatment of 17b with 18b, 9, and V-40, the potently reactive alpha-alkoxy bridgehead radical was genera …
The 6-membered 17b, prepared from d-ribose derivative 19, was designed to possess the caged orthoester structure with alpha-alkoxy selenide …
Identification and evolution of a plant cell wall specific glycoprotein glycosyl transferase, ExAD.
Møller SR, Yi X, Velásquez SM, Gille S, Hansen PLM, Poulsen CP, Olsen CE, Rejzek M, Parsons H, Yang Z, Wandall HH, Clausen H, Field RA, Pauly M, Estevez JM, Harholt J, Ulvskov P, Petersen BL. Møller SR, et al. Sci Rep. 2017 Mar 30;7:45341. doi: 10.1038/srep45341. Sci Rep. 2017. PMID: 28358137 Free PMC article.
In the conserved canonical extensin repeat, Ser-Hyp(4), serine and the consecutive C4-hydroxyprolines (Hyps) are substituted with an alpha-galactose and 1-5 beta- or alpha-linked arabinofuranoses (Arafs), respectively. ...
In the conserved canonical extensin repeat, Ser-Hyp(4), serine and the consecutive C4-hydroxyprolines (Hyps) are substituted with an …
Synthesis and Characterization of Water-Soluble Conjugated Oligoelectrolytes for Near-Infrared Fluorescence Biological Imaging.
Woo SJ, Park S, Jeong JE, Hong Y, Ku M, Kim BY, Jang IH, Heo SC, Wang T, Kim KH, Yang J, Kim JH, Woo HY. Woo SJ, et al. ACS Appl Mater Interfaces. 2016 Jun 29;8(25):15937-47. doi: 10.1021/acsami.6b04276. Epub 2016 Jun 16. ACS Appl Mater Interfaces. 2016. PMID: 27267787
The photoluminescence (PL) quantum efficiency is improved substantially by up to 27.8% in water by fabricating a vesicular complex, COE/v, with a block ionomer, poly[(ethylene oxide)-block-(sodium 2-acrylamido-2-methyl-1-propanesulfonate)]. ...The ex vivo and in vivo image …
The photoluminescence (PL) quantum efficiency is improved substantially by up to 27.8% in water by fabricating a vesicular complex, COE/v …
LC-MS-based quantification method for Achyranthes root saponins.
Kawahara Y, Hoshino T, Morimoto H, Shinizu T, Narukawa Y, Fuchino H, Kawahara N, Kiuchi F. Kawahara Y, et al. J Nat Med. 2016 Jan;70(1):102-6. doi: 10.1007/s11418-015-0942-4. Epub 2015 Oct 6. J Nat Med. 2016. PMID: 26439478
A liquid chromatography mass spectrometry (LC-MS) method was developed for simultaneous quantitative analysis of Achyranthes root saponins: chikusetsusaponins IVa (1) and V (2), achyranthosides B (3), C (4), D (5), E (6), and G (7), sulfachyranthosides B (8) and D (9), and …
A liquid chromatography mass spectrometry (LC-MS) method was developed for simultaneous quantitative analysis of Achyranthes root saponins: …
Alteration of complex sphingolipid composition and its physiological significance in yeast Saccharomyces cerevisiae lacking vacuolar ATPase.
Tani M, Toume M. Tani M, et al. Microbiology (Reading). 2015 Dec;161(12):2369-83. doi: 10.1099/mic.0.000187. Epub 2015 Sep 23. Microbiology (Reading). 2015. PMID: 26404656 Free article.
V-ATPase-deleted cells exhibited slow growth at pH 7.2, whereas the increase in MIPC levels was significantly enhanced when V-ATPase-deleted cells were incubated at pH 7.2. ...On the contrary, the growth rate of V-ATPase-deleted cells was moderately increased …
V-ATPase-deleted cells exhibited slow growth at pH 7.2, whereas the increase in MIPC levels was significantly enhanced when V- …
32 results