Kubbutat MHG - Search Results

1

Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases.

Cozza G, Fortuna M, Meggio F, Sarno S, Kubbutat MHG, Totzke F, Schaechtele C, Pinna LA, Olsufyeva EN, Preobrazhenskaya MN. Cozza G, et al. Among authors: kubbutat mhg. Biochemistry (Mosc). 2018 Oct;83(10):1222-1230. doi: 10.1134/S0006297918100073. Biochemistry (Mosc). 2018. PMID: 30472959 Free PMC article.

2

Cell lines expressing recombinant transmembrane domain-activated receptor kinases as tools for drug discovery.

Weber H, Müller D, Müller M, Ortiz A, Birkle M, Umber S, Ketterer C, Siedentopf O, Feger D, Totzke F, Kubbutat M, Schaechtele C, Ballmer-Hofer K, Ehlert JE, Graeser R. Weber H, et al. J Biomol Screen. 2014 Dec;19(10):1350-61. doi: 10.1177/1087057114552414. Epub 2014 Sep 26. J Biomol Screen. 2014. PMID: 25260782

3

Search for inhibitors of bacterial and human protein kinases among derivatives of diazepines[1,4] annelated with maleimide and indole cycles.

Danilenko VN, Simonov AY, Lakatosh SA, Kubbutat MH, Totzke F, Schächtele C, Elizarov SM, Bekker OB, Printsevskaya SS, Luzikov YN, Reznikova MI, Shtil AA, Preobrazhenskaya MN. Danilenko VN, et al. J Med Chem. 2008 Dec 25;51(24):7731-6. doi: 10.1021/jm800758s. J Med Chem. 2008. PMID: 19053831

4

Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties.

Shchekotikhin AE, Dezhenkova LG, Tsvetkov VB, Luzikov YN, Volodina YL, Tatarskiy VV Jr, Kalinina AA, Treshalin MI, Treshalina HM, Romanenko VI, Kaluzhny DN, Kubbutat M, Schols D, Pommier Y, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Eur J Med Chem. 2016 Apr 13;112:114-129. doi: 10.1016/j.ejmech.2016.01.050. Epub 2016 Feb 4. Eur J Med Chem. 2016. PMID: 26890118 Free PMC article.

5

Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors.

Barbosa ML, Lima LM, Tesch R, Sant'Anna CM, Totzke F, Kubbutat MH, Schächtele C, Laufer SA, Barreiro EJ. Barbosa ML, et al. Eur J Med Chem. 2014 Jan;71:1-14. doi: 10.1016/j.ejmech.2013.10.058. Epub 2013 Oct 31. Eur J Med Chem. 2014. PMID: 24269511

6

Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors.

Schlütke L, Immer M, Preu L, Totzke F, Schächtele C, Kubbutat MHG, Kunick C. Schlütke L, et al. Among authors: kubbutat mhg. Eur J Pharm Biopharm. 2018 May;126:89-94. doi: 10.1016/j.ejpb.2017.03.011. Epub 2017 Mar 15. Eur J Pharm Biopharm. 2018. PMID: 28315448

7

Cytotoxic effects of the anthraquinone derivatives 1'-deoxyrhodoptilometrin and (S)-(-)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp.

Wätjen W, Ebada SS, Bergermann A, Chovolou Y, Totzke F, Kubbutat MHG, Lin W, Proksch P. Wätjen W, et al. Among authors: kubbutat mhg. Arch Toxicol. 2017 Mar;91(3):1485-1495. doi: 10.1007/s00204-016-1787-7. Epub 2016 Jul 29. Arch Toxicol. 2017. PMID: 27473261

8

Assessing the target differentiation potential of imidazole-based protein kinase inhibitors.

Dimova D, Iyer P, Vogt M, Totzke F, Kubbutat MH, Schächtele C, Laufer S, Bajorath J. Dimova D, et al. J Med Chem. 2012 Dec 27;55(24):11067-71. doi: 10.1021/jm3014508. Epub 2012 Dec 11. J Med Chem. 2012. PMID: 23210446

9

Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells.

Limper C, Wang Y, Ruhl S, Wang Z, Lou Y, Totzke F, Kubbutat MH, Chovolou Y, Proksch P, Wätjen W. Limper C, et al. J Pharm Pharmacol. 2013 Sep;65(9):1393-408. doi: 10.1111/jphp.12107. Epub 2013 Jul 31. J Pharm Pharmacol. 2013. PMID: 23927478

10

7-(2-Anilinopyrimidin-4-yl)-1-benzazepin-2-ones Designed by a "Cut and Glue" Strategy Are Dual Aurora A/VEGF-R Kinase Inhibitors.

Karatas M, Chaikuad A, Berger B, Kubbutat MHG, Totzke F, Knapp S, Kunick C. Karatas M, et al. Among authors: kubbutat mhg. Molecules. 2021 Mar 14;26(6):1611. doi: 10.3390/molecules26061611. Molecules. 2021. PMID: 33799460 Free PMC article.

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