Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

59 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Translational learning from clinical studies predicts drug pharmacokinetics across patient populations.
Krauss M, Hofmann U, Schafmayer C, Igel S, Schlender J, Mueller C, Brosch M, von Schoenfels W, Erhart W, Schuppert A, Block M, Schaeffeler E, Boehmer G, Goerlitz L, Hoecker J, Lippert J, Kerb R, Hampe J, Kuepfer L, Schwab M. Krauss M, et al. Among authors: kuepfer l. NPJ Syst Biol Appl. 2017 Mar 28;3:11. doi: 10.1038/s41540-017-0012-5. eCollection 2017. NPJ Syst Biol Appl. 2017. PMID: 28649438 Free PMC article.
A computational systems biology software platform for multiscale modeling and simulation: integrating whole-body physiology, disease biology, and molecular reaction networks.
Eissing T, Kuepfer L, Becker C, Block M, Coboeken K, Gaub T, Goerlitz L, Jaeger J, Loosen R, Ludewig B, Meyer M, Niederalt C, Sevestre M, Siegmund HU, Solodenko J, Thelen K, Telle U, Weiss W, Wendl T, Willmann S, Lippert J. Eissing T, et al. Among authors: kuepfer l. Front Physiol. 2011 Feb 24;2:4. doi: 10.3389/fphys.2011.00004. eCollection 2011. Front Physiol. 2011. PMID: 21483730 Free PMC article.
Integrating cellular metabolism into a multiscale whole-body model.
Krauss M, Schaller S, Borchers S, Findeisen R, Lippert J, Kuepfer L. Krauss M, et al. Among authors: kuepfer l. PLoS Comput Biol. 2012;8(10):e1002750. doi: 10.1371/journal.pcbi.1002750. Epub 2012 Oct 25. PLoS Comput Biol. 2012. PMID: 23133351 Free PMC article.
Development of a physiologically based computational kidney model to describe the renal excretion of hydrophilic agents in rats.
Niederalt C, Wendl T, Kuepfer L, Claassen K, Loosen R, Willmann S, Lippert J, Schultze-Mosgau M, Winkler J, Burghaus R, Bräutigam M, Pietsch H, Lengsfeld P. Niederalt C, et al. Among authors: kuepfer l. Front Physiol. 2013 Jan 24;3:494. doi: 10.3389/fphys.2012.00494. eCollection 2012. Front Physiol. 2013. PMID: 23355822 Free PMC article.
A mechanistic, model-based approach to safety assessment in clinical development.
Lippert J, Brosch M, von Kampen O, Meyer M, Siegmund HU, Schafmayer C, Becker T, Laffert B, Görlitz L, Schreiber S, Neuvonen PJ, Niemi M, Hampe J, Kuepfer L. Lippert J, et al. Among authors: kuepfer l. CPT Pharmacometrics Syst Pharmacol. 2012 Nov 7;1(11):e13. doi: 10.1038/psp.2012.14. CPT Pharmacometrics Syst Pharmacol. 2012. PMID: 23835795 Free PMC article.
Spatio-temporal simulation of first pass drug perfusion in the liver.
Schwen LO, Krauss M, Niederalt C, Gremse F, Kiessling F, Schenk A, Preusser T, Kuepfer L. Schwen LO, et al. Among authors: kuepfer l. PLoS Comput Biol. 2014 Mar 13;10(3):e1003499. doi: 10.1371/journal.pcbi.1003499. eCollection 2014 Mar. PLoS Comput Biol. 2014. PMID: 24625393 Free PMC article.
Clinical translation in the virtual liver network.
Kuepfer L, Kerb R, Henney AM. Kuepfer L, et al. CPT Pharmacometrics Syst Pharmacol. 2014 Jul 30;3(7):e127. doi: 10.1038/psp.2014.25. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25076067 Free PMC article.
59 results