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Excessive portal venous supply of long-chain free fatty acids to the liver, leading to hypothalamus-pituitary-adrenal-axis and sympathetic activation as a key to the development of syndrome X. A proposed concept for the induction of syndrome X.
Benthem L, Kuipers F, Steffens AB, Scheurink AJ. Benthem L, et al. Among authors: kuipers f. Ann N Y Acad Sci. 1999 Nov 18;892:308-11. doi: 10.1111/j.1749-6632.1999.tb07804.x. Ann N Y Acad Sci. 1999. PMID: 10842671 Review. No abstract available.
Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048.
van Dijk TH, van der Sluijs FH, Wiegman CH, Baller JF, Gustafson LA, Burger HJ, Herling AW, Kuipers F, Meijer AJ, Reijngoud DJ. van Dijk TH, et al. Among authors: kuipers f. J Biol Chem. 2001 Jul 13;276(28):25727-35. doi: 10.1074/jbc.M101223200. Epub 2001 May 9. J Biol Chem. 2001. PMID: 11346646 Free article.
483 results