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Page 1
Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes.
Del Vecchio G, Li Q, Li W, Thamotharan S, Tosevska A, Morselli M, Sung K, Janzen C, Zhou X, Pellegrini M, Devaskar SU. Del Vecchio G, et al. Among authors: sung k. Epigenetics. 2021 Jun;16(6):642-661. doi: 10.1080/15592294.2020.1816774. Epub 2020 Oct 13. Epigenetics. 2021. PMID: 33045922 Free PMC article.
Employing a novel deconvolution methodology, we found that during the first trimester, placenta-specific DNA increased prior to the subsequent development of gestational diabetes with no change in patients with preeclampsia while decreasing with maternal obesity. ...We con …
Employing a novel deconvolution methodology, we found that during the first trimester, placenta-specific DNA increased prior to the s …
Early pregnancy imaging predicts ischemic placental disease.
Lee B, Janzen C, Aliabadi AR, Lei MYY, Wu H, Liu D, Vangala SS, Devaskar SU, Sung K. Lee B, et al. Among authors: sung k. Placenta. 2023 Sep 7;140:90-99. doi: 10.1016/j.placenta.2023.07.297. Epub 2023 Jul 31. Placenta. 2023. PMID: 37549442 Free PMC article.
METHODS: In a single-center prospective cohort study, 199 women were recruited from antenatal clinics between February 2017 and February 2019. Maternal magnetic resonance imaging (MRI) studies of the placenta were temporally conducted at two timepoints: 14-16 weeks gestati …
METHODS: In a single-center prospective cohort study, 199 women were recruited from antenatal clinics between February 2017 and February 201 …
Human Placenta Blood Flow During Early Gestation With Pseudocontinuous Arterial Spin Labeling MRI.
Liu D, Shao X, Danyalov A, Chanlaw T, Masamed R, Wang DJJ, Janzen C, Devaskar SU, Sung K. Liu D, et al. Among authors: sung k. J Magn Reson Imaging. 2020 Apr;51(4):1247-1257. doi: 10.1002/jmri.26944. Epub 2019 Nov 4. J Magn Reson Imaging. 2020. PMID: 31680405 Free PMC article.
BACKGROUND: Noninvasive measurement of placental blood flow is the major technical challenge for predicting ischemic placenta (IPD). Pseudocontinuous arterial spin labeling (pCASL) MRI was recently shown to be promising, but the potential value in predicting the subsequenc …
BACKGROUND: Noninvasive measurement of placental blood flow is the major technical challenge for predicting ischemic placenta (IPD). …
Evaluation of Spatial Attentive Deep Learning for Automatic Placental Segmentation on Longitudinal MRI.
Liu Y, Zabihollahy F, Yan R, Lee B, Janzen C, Devaskar SU, Sung K. Liu Y, et al. Among authors: sung k. J Magn Reson Imaging. 2023 May;57(5):1533-1540. doi: 10.1002/jmri.28403. Epub 2022 Aug 16. J Magn Reson Imaging. 2023. PMID: 37021577 Free PMC article.
BACKGROUND: Automated segmentation of the placenta by MRI in early pregnancy may help predict normal and aberrant placenta function, which could improve the efficiency of placental assessment and the prediction of pregnancy outcomes. ...DATA CONCLUSIONS: SADL can au …
BACKGROUND: Automated segmentation of the placenta by MRI in early pregnancy may help predict normal and aberrant placenta fun …
A Description of the Imaging Innovations for Placental Assessment in Response to Environmental Pollution Study.
Janzen C, Lei MYY, Lee BR, Vangala S, DelRosario I, Meng Q, Ritz B, Liu J, Jerrett M, Chanlaw T, Choi S, Aliabadi A, Fortes PA, Sullivan PS, Murphy A, Vecchio GD, Thamotharan S, Sung K, Devaskar SU. Janzen C, et al. Among authors: sung k. Am J Perinatol. 2024 May;41(S 01):e853-e862. doi: 10.1055/a-1961-2059. Epub 2022 Oct 14. Am J Perinatol. 2024. PMID: 36241211 Free PMC article.
Maternal biospecimens (serum, plasma, and urine) at antepartum study visits and delivery specimens (placenta, cord, and maternal blood) were collected, processed, and stored. ...MRI was acceptable and feasible for the study of the human placenta in vivo.. . Function …
Maternal biospecimens (serum, plasma, and urine) at antepartum study visits and delivery specimens (placenta, cord, and maternal bloo …
3D R2* mapping of the placenta during early gestation using free-breathing multiecho stack-of-radial MRI at 3T.
Armstrong T, Liu D, Martin T, Masamed R, Janzen C, Wong C, Chanlaw T, Devaskar SU, Sung K, Wu HH. Armstrong T, et al. Among authors: sung k. J Magn Reson Imaging. 2019 Jan;49(1):291-303. doi: 10.1002/jmri.26203. Epub 2018 Aug 24. J Magn Reson Imaging. 2019. PMID: 30142239 Free PMC article.

At 19-23 weeks, the CV was significantly lower (P < 0.001) for anterior (0.49 0.08) than posterior (0.67 0.11) placentas. One IPD subject had a lower mean R2* than normal subjects at both GA ranges (Z<-2). DATA CONCLUSION: FB radial provides accurate and repeatable 3

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At 19-23 weeks, the CV was significantly lower (P < 0.001) for anterior (0.49 0.08) than posterior (0.67 0.11) placentas. One IPD

…
Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking.
Martin T, Janzen C, Li X, Del Rosario I, Chanlaw T, Choi S, Armstrong T, Masamed R, Wu HH, Devaskar SU, Sung K. Martin T, et al. Among authors: sung k. Diagnostics (Basel). 2020 Oct 19;10(10):840. doi: 10.3390/diagnostics10100840. Diagnostics (Basel). 2020. PMID: 33086473 Free PMC article.
Magnetic resonance imaging (MRI) is a promising non-invasive imaging technique that can be safely used to study placental development and function. However, studies of the human placenta performed by MRI are limited by uterine motion and motion in the uterus during MRI rem …
Magnetic resonance imaging (MRI) is a promising non-invasive imaging technique that can be safely used to study placental development and fu …
Measuring human placental blood flow with multidelay 3D GRASE pseudocontinuous arterial spin labeling at 3T.
Shao X, Liu D, Martin T, Chanlaw T, Devaskar SU, Janzen C, Murphy AM, Margolis D, Sung K, Wang DJJ. Shao X, et al. Among authors: sung k. J Magn Reson Imaging. 2018 Jun;47(6):1667-1676. doi: 10.1002/jmri.25893. Epub 2017 Nov 14. J Magn Reson Imaging. 2018. PMID: 29135072 Free PMC article.
BACKGROUND: Placenta influences the health of both a woman and her fetus during pregnancy. Maternal blood supply to placenta can be measured noninvasively using arterial spin labeling (ASL). ...
BACKGROUND: Placenta influences the health of both a woman and her fetus during pregnancy. Maternal blood supply to placenta c …
Maternal dietary patterns and placental outcomes among pregnant women in Los Angeles.
Meng Q, Del Rosario I, Sung K, Janzen C, Devaskar SU, Carpenter CL, Ritz B. Meng Q, et al. Among authors: sung k. Placenta. 2024 Jan;145:72-79. doi: 10.1016/j.placenta.2023.12.002. Epub 2023 Dec 5. Placenta. 2024. PMID: 38100961 Free article.
We conducted T(2)-weighted magnetic resonance imaging (MRI) in mid-pregnancy (1st during 14-17 and 2nd during 19-24 gestational weeks) to evaluate placental volume (cm(3)) and we measured placenta weight (g) at delivery. We estimated change and 95 % confidence interval (CI …
We conducted T(2)-weighted magnetic resonance imaging (MRI) in mid-pregnancy (1st during 14-17 and 2nd during 19-24 gestational weeks) to ev …