Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery.
Wallace NS, Gadbery JE, Cohen CI, Kendall AK, Jackson LP.
Wallace NS, et al.
bioRxiv [Preprint]. 2023 Jul 18:2023.07.18.549521. doi: 10.1101/2023.07.18.549521.
bioRxiv. 2023.
PMID: 37502979
Free PMC article.
Updated.
Preprint.
AP-4 vesicles originate at the trans -Golgi network (TGN) and target the delivery of ATG9A, a scramblase required for autophagosome biogenesis, to the cell periphery. Using in silico methods, we identified a putative L C3-Interacting R egion (LIR) motif in tepsin. B …
AP-4 vesicles originate at the trans -Golgi network (TGN) and target the delivery of ATG9A, a scramblase required for autophagosome biogenes …