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Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer.
Ortiz-Cuaran S, Swalduz A, Foy JP, Marteau S, Morel AP, Fauvet F, De Souza G, Michon L, Boussageon M, Gadot N, Godefroy M, Léon S, Tortereau A, Mourksi NE, Leonce C, Albaret MA, Dongre A, Vanbervliet B, Robert M, Tonon L, Pommier RM, Hofman V, Attignon V, Boyault S, Audoynaud C, Auclair J, Bouquet F, Wang Q, Ménétrier-Caux C, Pérol M, Caux C, Hofman P, Lantuejoul S, Puisieux A, Saintigny P. Ortiz-Cuaran S, et al. Among authors: leon s. Eur J Cancer. 2022 Jul;169:106-122. doi: 10.1016/j.ejca.2022.03.038. Epub 2022 May 9. Eur J Cancer. 2022. PMID: 35550950
Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer.
Cassier PA, Navaridas R, Bellina M, Rama N, Ducarouge B, Hernandez-Vargas H, Delord JP, Lengrand J, Paradisi A, Fattet L, Garin G, Gheit H, Dalban C, Pastushenko I, Neves D, Jelin R, Gadot N, Braissand N, Léon S, Degletagne C, Matias-Guiu X, Devouassoux-Shisheboran M, Mery-Lamarche E, Allard J, Zindy E, Decaestecker C, Salmon I, Perol D, Dolcet X, Ray-Coquard I, Blanpain C, Bernet A, Mehlen P. Cassier PA, et al. Among authors: leon s. Nature. 2023 Aug;620(7973):409-416. doi: 10.1038/s41586-023-06367-z. Epub 2023 Aug 2. Nature. 2023. PMID: 37532934 Free PMC article. Clinical Trial.
Fusion-negative rhabdomyosarcoma 3D organoids to predict effective drug combinations: A proof-of-concept on cell death inducers.
Savary C, Luciana L, Huchedé P, Tourbez A, Coquet C, Broustal M, Lopez Gonzalez A, Deligne C, Diot T, Naret O, Costa M, Meynard N, Barbet V, Müller K, Tonon L, Gadot N, Degletagne C, Attignon V, Léon S, Vanbelle C, Bomane A, Rochet I, Mournetas V, Oliveira L, Rinaudo P, Bergeron C, Dutour A, Cordier-Bussat M, Roch A, Brandenberg N, El Zein S, Watson S, Orbach D, Delattre O, Dijoud F, Corradini N, Picard C, Maucort-Boulch D, Le Grand M, Pasquier E, Blay JY, Castets M, Broutier L. Savary C, et al. Among authors: leon s. Cell Rep Med. 2023 Dec 19;4(12):101339. doi: 10.1016/j.xcrm.2023.101339. Cell Rep Med. 2023. PMID: 38118405 Free PMC article.
Targeting netrin-1/DCC interaction in diffuse large B-cell and mantle cell lymphomas.
Broutier L, Creveaux M, Vial J, Tortereau A, Delcros JG, Chazot G, McCarron MJ, Léon S, Pangault C, Gadot N, Colombe A, Boulland ML, Blachier J, Marie JC, Traverse-Glehen A, Donzé O, Chassagne-Clément C, Salles G, Tarte K, Mehlen P, Castets M. Broutier L, et al. Among authors: leon s. EMBO Mol Med. 2016 Feb 1;8(2):96-104. doi: 10.15252/emmm.201505480. EMBO Mol Med. 2016. PMID: 26882243 Free PMC article.
The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death.
Vial J, Royet A, Cassier P, Tortereau A, Dinvaut S, Maillet D, Gratadou-Hupon L, Creveaux M, Sadier A, Tondeur G, Léon S, Depaepe L, Pantalacci S, de la Fouchardière A, Micheau O, Dalle S, Laudet V, Mehlen P, Castets M. Vial J, et al. Among authors: leon s. Cell Death Differ. 2019 Mar;26(3):443-454. doi: 10.1038/s41418-018-0128-1. Epub 2018 May 31. Cell Death Differ. 2019. PMID: 29855541 Free PMC article.
The TLR3 L412F polymorphism prevents TLR3-mediated tumor cell death induction in pediatric sarcomas.
Bisaccia J, Meyer S, Bertrand-Chapel A, Hecquet Q, Barbet V, Kaniewski B, Léon S, Gadot N, Rochet I, Fajnorova I, Leblond P, Cordier-Bussat M, Corradini N, Vasiljevic A, Billaud M, Picard C, Broutier L, Gallerne C, Dutour A, Blay JY, Castets M. Bisaccia J, et al. Among authors: leon s. Cell Death Discov. 2023 Jul 7;9(1):230. doi: 10.1038/s41420-023-01513-y. Cell Death Discov. 2023. PMID: 37414800 Free PMC article.
836 results