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NR4A transcription factors limit CAR T cell function in solid tumours.
Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A. Chen J, et al. Among authors: lopez moyado if. Nature. 2019 Mar;567(7749):530-534. doi: 10.1038/s41586-019-0985-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814732 Free PMC article.
TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion.
Seo H, Chen J, González-Avalos E, Samaniego-Castruita D, Das A, Wang YH, López-Moyado IF, Georges RO, Zhang W, Onodera A, Wu CJ, Lu LF, Hogan PG, Bhandoola A, Rao A. Seo H, et al. Among authors: lopez moyado if. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12410-12415. doi: 10.1073/pnas.1905675116. Epub 2019 May 31. Proc Natl Acad Sci U S A. 2019. PMID: 31152140 Free PMC article.
Active DNA demethylation damages DNA.
López-Moyado IF, Rao A. López-Moyado IF, et al. Science. 2022 Dec 2;378(6623):948-949. doi: 10.1126/science.adf3171. Epub 2022 Dec 1. Science. 2022. PMID: 36454845 Free PMC article.
Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch.
Yuita H, López-Moyado IF, Jeong H, Cheng AX, Scott-Browne J, An J, Nakayama T, Onodera A, Ko M, Rao A. Yuita H, et al. Among authors: lopez moyado if. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2214824120. doi: 10.1073/pnas.2214824120. Epub 2023 Feb 1. Proc Natl Acad Sci U S A. 2023. PMID: 37406303 Free PMC article.
15 results