Lützen A - Search Results

1

Molecular characterisation of long-acting insulin analogues in comparison with human insulin, IGF-1 and insulin X10.

Hansen BF, Glendorf T, Hegelund AC, Lundby A, Lützen A, Slaaby R, Stidsen CE. Hansen BF, et al. Among authors: lutzen a. PLoS One. 2012;7(5):e34274. doi: 10.1371/journal.pone.0034274. Epub 2012 May 8. PLoS One. 2012. PMID: 22590494 Free PMC article.

2

Surface-expressed insulin receptors as well as IGF-I receptors both contribute to the mitogenic effects of human insulin and its analogues.

Lundby A, Bolvig P, Hegelund AC, Hansen BF, Worm J, Lützen A, Billestrup N, Bonnesen C, Oleksiewicz MB. Lundby A, et al. Among authors: lutzen a. J Appl Toxicol. 2015 Jul;35(7):842-50. doi: 10.1002/jat.3082. Epub 2014 Nov 21. J Appl Toxicol. 2015. PMID: 25413577

3

A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues.

Baricevic I, Jones DR, Roberts DL, Lutzen A, Lundby A, Worm J, Hansen BF, Renehan AG. Baricevic I, et al. Among authors: lutzen a. Carcinogenesis. 2015 Sep;36(9):1040-50. doi: 10.1093/carcin/bgv071. Epub 2015 May 30. Carcinogenesis. 2015. PMID: 26026165 Free PMC article.

4

Activation of insulin receptors and IGF-1 receptors in COLO-205 colon cancer xenografts by insulin and insulin analogue X10 does not enhance growth under normo- or hypoglycaemic conditions.

Hvid H, Jørgensen MS, Blume N, Slaaby R, Lützen A, Hansen BF. Hvid H, et al. Among authors: lutzen a. Diabetologia. 2018 Nov;61(11):2447-2457. doi: 10.1007/s00125-018-4684-1. Epub 2018 Jul 12. Diabetologia. 2018. PMID: 30003309

5

Increased insulin receptor binding and increased IGF-1 receptor binding are linked with increased growth of L6hIR cell xenografts in vivo.

Hvid H, Glendorf T, Brandt J, Slaaby R, Lützen A, Kristensen K, Hansen BF. Hvid H, et al. Among authors: lutzen a. Sci Rep. 2020 Apr 29;10(1):7247. doi: 10.1038/s41598-020-64318-4. Sci Rep. 2020. PMID: 32350367 Free PMC article.

6

Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing.

Nishimura E, Pridal L, Glendorf T, Hansen BF, Hubálek F, Kjeldsen T, Kristensen NR, Lützen A, Lyby K, Madsen P, Pedersen TÅ, Ribel-Madsen R, Stidsen CE, Haahr H. Nishimura E, et al. Among authors: lutzen a. BMJ Open Diabetes Res Care. 2021 Aug;9(1):e002301. doi: 10.1136/bmjdrc-2021-002301. BMJ Open Diabetes Res Care. 2021. PMID: 34413118 Free PMC article. Clinical Trial.

7

Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor.

Ørstrup LH, Slaaby R, Rasch MG, Rasmussen N, Lund S, Brandt J, Schluckebier G, Wang Z, Lützen A, Pedersen TÅ, Hvid H, Hansen BF, Blume N. Ørstrup LH, et al. Among authors: lutzen a. J Immunol Methods. 2019 Feb;465:20-26. doi: 10.1016/j.jim.2018.11.014. Epub 2018 Nov 27. J Immunol Methods. 2019. PMID: 30500329 Free article.

8

Cadmium inhibits human DNA mismatch repair in vivo.

Lützen A, Liberti SE, Rasmussen LJ. Lützen A, et al. Biochem Biophys Res Commun. 2004 Aug 13;321(1):21-5. doi: 10.1016/j.bbrc.2004.06.102. Biochem Biophys Res Commun. 2004. PMID: 15358209

9

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA.

Nielsen FC, Jäger AC, Lützen A, Bundgaard JR, Rasmussen LJ. Nielsen FC, et al. Among authors: lutzen a. Oncogene. 2004 Feb 19;23(7):1457-68. doi: 10.1038/sj.onc.1207265. Oncogene. 2004. PMID: 14676842

10

Nuclear translocation contributes to regulation of DNA excision repair activities.

Knudsen NØ, Andersen SD, Lützen A, Nielsen FC, Rasmussen LJ. Knudsen NØ, et al. Among authors: lutzen a. DNA Repair (Amst). 2009 Jun 4;8(6):682-9. doi: 10.1016/j.dnarep.2009.03.005. Epub 2009 Apr 18. DNA Repair (Amst). 2009. PMID: 19376751 Review.

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