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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1938 1
1947 2
1949 1
1950 4
1951 2
1952 4
1953 1
1954 5
1955 2
1956 2
1957 1
1958 3
1959 3
1960 1
1961 4
1962 6
1963 7
1964 18
1965 21
1966 20
1967 27
1968 18
1969 19
1970 14
1971 21
1972 22
1973 21
1974 17
1975 19
1976 17
1977 22
1978 14
1979 16
1980 14
1981 7
1982 11
1983 8
1984 11
1985 11
1986 7
1987 14
1988 6
1989 8
1990 9
1991 9
1992 10
1993 12
1994 12
1995 9
1996 7
1997 10
1998 13
1999 14
2000 23
2001 21
2002 17
2003 17
2004 14
2005 13
2006 10
2007 11
2008 16
2009 11
2010 23
2011 18
2012 15
2013 24
2014 21
2015 31
2016 27
2017 20
2018 16
2019 27
2020 27
2021 23
2022 25
2023 20
2024 9

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986 results

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Page 1
Rare sugar L-sorbose exerts antitumor activity by impairing glucose metabolism.
Xu HL, Zhou X, Chen S, Xu S, Li Z, Nakanishi H, Gao XD. Xu HL, et al. Commun Biol. 2023 Mar 11;6(1):259. doi: 10.1038/s42003-023-04638-z. Commun Biol. 2023. PMID: 36906698 Free PMC article.
They are structural isomers of dietary sugars, but hardly be metabolized. Here, we report that rare sugar L-sorbose induces apoptosis in various cancer cells. As a C-3 epimer of D-fructose, L-sorbose is internalized via the transporter GLUT5 and phosph …
They are structural isomers of dietary sugars, but hardly be metabolized. Here, we report that rare sugar L-sorbose induces ap …
L-Sorbose-1-phosphate reductase.
Anderson RL, Simkins RA. Anderson RL, et al. Methods Enzymol. 1982;89 Pt D:248-51. doi: 10.1016/s0076-6879(82)89044-7. Methods Enzymol. 1982. PMID: 6755171 No abstract available.
Combined engineering of l-sorbose dehydrogenase and fermentation optimization to increase 2-keto-l-gulonic acid production in Escherichia coli.
Li D, Wang X, Qin Z, Yu S, Chen J, Zhou J. Li D, et al. Bioresour Technol. 2023 Mar;372:128672. doi: 10.1016/j.biortech.2023.128672. Epub 2023 Jan 23. Bioresour Technol. 2023. PMID: 36702324
Improvement of the enzyme's activity through engineering could benefit 2-KLG production. This study aimed to conduct a semi-rational design of l-sorbose dehydrogenase (SDH) through structure-directed, to screen mutants that could enhance the 2-KLG titer. ...Finally, …
Improvement of the enzyme's activity through engineering could benefit 2-KLG production. This study aimed to conduct a semi-rational design …
L-Sorbose utilization by virulent Escherichia coli and Shigella: different metabolic adaptation of pathotypes.
Lehmacher A, Bockemühl J. Lehmacher A, et al. Int J Med Microbiol. 2007 Jul;297(4):245-54. doi: 10.1016/j.ijmm.2007.01.007. Epub 2007 Mar 26. Int J Med Microbiol. 2007. PMID: 17382590 Free article.
This suggests an association of pathomechanism with the capability to degrade L-Sorbose. The use of a selective agar, containing L-Sorbose and antibiotics, facilitated the isolation of L-Sorbose-non-utilizing ETEC from stool specimens of …
This suggests an association of pathomechanism with the capability to degrade L-Sorbose. The use of a selective agar, containi …
Enhanced 2-keto-L-gulonic acid production by applying L-sorbose-tolerant helper strain in the co-culture system.
Mandlaa, Sun Z, Wang R, Han X, Xu H, Yang W. Mandlaa, et al. AMB Express. 2018 Feb 28;8(1):30. doi: 10.1186/s13568-018-0562-y. AMB Express. 2018. PMID: 29492704 Free PMC article.
2-Keto-L-gulonic acid (the precursor of vitamin C) is bio-converted from L-sorbose by mixed fermentation of Ketogulonicigenium vulgare and a helper strain. The helper strain promotes the conversion of 2-KLG by enhancing the growth of K. vulgare, but its growth is gr …
2-Keto-L-gulonic acid (the precursor of vitamin C) is bio-converted from L-sorbose by mixed fermentation of Ketogulonicigenium …
L-Sorbose phosphorylation in Escherichia coli K-12.
Slater AC, Jones-Mortimer MC, Kornberg HL. Slater AC, et al. Biochim Biophys Acta. 1981 Aug 20;646(2):365-7. doi: 10.1016/0005-2736(81)90346-1. Biochim Biophys Acta. 1981. PMID: 7028117
L-Sorbose is phosphorylated by Escherichia coli by two distinct Enzymes II of the phosphoenolpyruvate-dependent phosphotransferase system. ...L-Sorbose induces neither of these Enzymes II, but sorbose inhibits the growth of strains expressing ei …
L-Sorbose is phosphorylated by Escherichia coli by two distinct Enzymes II of the phosphoenolpyruvate-dependent phosphotransfe …
Overcoming NADPH product inhibition improves D-sorbitol conversion to L-sorbose.
Kim TS, Gao H, Li J, Kalia VC, Muthusamy K, Sohng JK, Kim IW, Lee JK. Kim TS, et al. Sci Rep. 2019 Jan 28;9(1):815. doi: 10.1038/s41598-018-37401-0. Sci Rep. 2019. PMID: 30692560 Free PMC article.
Gluconobacter oxydans sorbitol dehydrogenase (GoSLDH) exhibits a higher catalytic efficiency than other L-sorbose producing enzymes. During the reaction catalysed by GoSLDH, NADP(+) is reduced to NADPH and D-sorbitol is oxidized to L-sorbose. ...Theref …
Gluconobacter oxydans sorbitol dehydrogenase (GoSLDH) exhibits a higher catalytic efficiency than other L-sorbose producing en …
A two-step strategy for the preparation of 6-deoxy-l-sorbose.
Wen L, Huang K, Zheng Y, Liu Y, Zhu H, Wang PG. Wen L, et al. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4358-61. doi: 10.1016/j.bmcl.2016.03.083. Epub 2016 Mar 25. Bioorg Med Chem Lett. 2016. PMID: 27485385 Free PMC article.
The resultant 6-deoxy-l-sorbose 1-phosphate was purified by silver nitrate precipitation method. In the second reaction step, the phosphate group of the 6-deoxy-l-sorbose 1-phosphate was hydrolyzed with acid phosphatase (AphA) to produce 6-deoxy-l …
The resultant 6-deoxy-l-sorbose 1-phosphate was purified by silver nitrate precipitation method. In the second reaction step, …
Biosynthesis of l-Sorbose and l-Psicose Based on C-C Bond Formation Catalyzed by Aldolases in an Engineered Corynebacterium glutamicum Strain.
Yang J, Li J, Men Y, Zhu Y, Zhang Y, Sun Y, Ma Y. Yang J, et al. Appl Environ Microbiol. 2015 Jul;81(13):4284-94. doi: 10.1128/AEM.00208-15. Epub 2015 Apr 17. Appl Environ Microbiol. 2015. PMID: 25888171 Free PMC article.
Subsequently, a "one-pot" reaction based on BGatY and fructose-1-phosphatase (YqaB) generated 378 mg/liter l-psicose and 199 mg/liter l-sorbose from dihydroxyacetone-phosphate (DHAP) and l-glyceraldehyde. ...Finally, fed-batch culture of strain SY14(pXFTY) produced …
Subsequently, a "one-pot" reaction based on BGatY and fructose-1-phosphatase (YqaB) generated 378 mg/liter l-psicose and 199 mg/liter l …
L-Sorbose metabolism in Klebsiella pneumoniae and Sor+ derivatives of Escherichia coli K-12 and chemotaxis toward sorbose.
Sprenger GA, Lengeler JW. Sprenger GA, et al. J Bacteriol. 1984 Jan;157(1):39-45. doi: 10.1128/jb.157.1.39-45.1984. J Bacteriol. 1984. PMID: 6361004 Free PMC article.
L-Sorbose degradation in Klebsiella pneumoniae was shown to follow the pathway L-sorbose leads to L-sorbose-1-phosphate leads to D-glucitol-6-phosphate leads to D-fructose-6-phosphate. ...Two soluble enzymes, an L-sorbose-1- …
L-Sorbose degradation in Klebsiella pneumoniae was shown to follow the pathway L-sorbose leads to L-so …
986 results