Biosynthesis of heparin. Enzymatic sulfation of pentasaccharides.
Kusche M, Oscarsson LG, Reynertson R, Rodén L, Lindahl U.
Kusche M, et al. Among authors: lindahl u.
J Biol Chem. 1991 Apr 25;266(12):7400-9.
J Biol Chem. 1991.
PMID: 1902219
Free article.
The antithrombin-binding region, essential for the blood anticoagulant activity of heparin, has been identified as a pentasaccharide sequence with the predominant structure GlcNR(6-OSO3)-GlcA-GlcNSO3(3,6-di-OSO3)-++ +IdoA(2-OSO3)-GlcNSO3(6-OSO3) (where R represents either a sulfa …
The antithrombin-binding region, essential for the blood anticoagulant activity of heparin, has been identified as a pentasaccharide sequenc …