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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1983 1
1987 1
1988 1
1990 1
1992 1
1993 3
1995 4
1996 5
1997 4
1998 3
1999 2
2000 4
2001 4
2002 4
2003 6
2004 7
2005 9
2006 8
2007 10
2008 7
2009 2
2010 4
2011 16
2012 17
2013 9
2014 9
2015 8
2016 10
2017 17
2018 26
2019 20
2020 20
2021 21
2022 17
2023 21
2024 5

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273 results

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Page 1
Omega-3 fatty acids in inflammation and autoimmune diseases.
Simopoulos AP. Simopoulos AP. J Am Coll Nutr. 2002 Dec;21(6):495-505. doi: 10.1080/07315724.2002.10719248. J Am Coll Nutr. 2002. PMID: 12480795 Review.
Animal experiments and clinical intervention studies indicate that omega-3 fatty acids have anti-inflammatory properties and, therefore, might be useful in the management of inflammatory and autoimmune diseases. Coronary heart disease, major depression, aging and cancer ar …
Animal experiments and clinical intervention studies indicate that omega-3 fatty acids have anti-inflammatory properties and, therefore, mig …
Blocking LTB(4) signaling-mediated TAMs recruitment by Rhizoma Coptidis sensitizes lung cancer to immunotherapy.
Yan J, Zhu J, Li X, Yang R, Xiao W, Huang C, Zheng C. Yan J, et al. Phytomedicine. 2023 Oct;119:154968. doi: 10.1016/j.phymed.2023.154968. Epub 2023 Jul 22. Phytomedicine. 2023. PMID: 37531900
Western blot was performed to analyze the expression of Leukotriene A4 hydrolase (LTA4H) and LTB(4) receptor 1 (BLT1) in harvested lung cancer tissues. The impact of blocking leukotriene B(4) (LTB(4)) signaling by RC on the recruitment of M2 macrophages was a …
Western blot was performed to analyze the expression of Leukotriene A4 hydrolase (LTA4H) and LTB(4) receptor 1 (BLT1) in harvested lu …
Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung.
Schupp JC, Adams TS, Cosme C Jr, Raredon MSB, Yuan Y, Omote N, Poli S, Chioccioli M, Rose KA, Manning EP, Sauler M, DeIuliis G, Ahangari F, Neumark N, Habermann AC, Gutierrez AJ, Bui LT, Lafyatis R, Pierce RW, Meyer KB, Nawijn MC, Teichmann SA, Banovich NE, Kropski JA, Niklason LE, Pe'er D, Yan X, Homer RJ, Rosas IO, Kaminski N. Schupp JC, et al. Circulation. 2021 Jul 27;144(4):286-302. doi: 10.1161/CIRCULATIONAHA.120.052318. Epub 2021 May 25. Circulation. 2021. PMID: 34030460 Free PMC article.
Plectin in Cancer: From Biomarker to Therapeutic Target.
Perez SM, Brinton LT, Kelly KA. Perez SM, et al. Cells. 2021 Aug 30;10(9):2246. doi: 10.3390/cells10092246. Cells. 2021. PMID: 34571895 Free PMC article. Review.
The cytolinker and scaffolding protein, plectin, has emerged as a potent driver of malignant hallmarks in many human cancers due to its involvement in various cellular activities contributing to tumorigenesis, including cancer cell proliferation, adhesion, migration …
The cytolinker and scaffolding protein, plectin, has emerged as a potent driver of malignant hallmarks in many human cancers due to i …
The role of the LTB(4)-BLT1 axis in chemotactic gradient sensing and directed leukocyte migration.
Subramanian BC, Majumdar R, Parent CA. Subramanian BC, et al. Semin Immunol. 2017 Oct;33:16-29. doi: 10.1016/j.smim.2017.07.002. Semin Immunol. 2017. PMID: 29042024 Free PMC article. Review.
In this review, we summarize the essential steps leading to the production of LTB(4) in leukocytes. We discuss the recent findings on the exosomal packaging and transport of LTB(4) in the context of chemotactic gradients formation and regulation of leukocyte recruit …
In this review, we summarize the essential steps leading to the production of LTB(4) in leukocytes. We discuss the recent findings on …
Germinal Centers Determine the Prognostic Relevance of Tertiary Lymphoid Structures and Are Impaired by Corticosteroids in Lung Squamous Cell Carcinoma.
Siliņa K, Soltermann A, Attar FM, Casanova R, Uckeley ZM, Thut H, Wandres M, Isajevs S, Cheng P, Curioni-Fontecedro A, Foukas P, Levesque MP, Moch H, Linē A, van den Broek M. Siliņa K, et al. Cancer Res. 2018 Mar 1;78(5):1308-1320. doi: 10.1158/0008-5472.CAN-17-1987. Epub 2017 Dec 26. Cancer Res. 2018. PMID: 29279354 Free article.
In solid tumors, the presence of lymph node-like structures called tertiary lymphoid structures (TLS) is associated with improved patient survival. However, little is known about how TLS develop in cancer, how their function affects survival, and whether they are affected …
In solid tumors, the presence of lymph node-like structures called tertiary lymphoid structures (TLS) is associated with improved patient su …
Ceramide-rich microdomains facilitate nuclear envelope budding for non-conventional exosome formation.
Arya SB, Chen S, Jordan-Javed F, Parent CA. Arya SB, et al. Nat Cell Biol. 2022 Jul;24(7):1019-1028. doi: 10.1038/s41556-022-00934-8. Epub 2022 Jun 23. Nat Cell Biol. 2022. PMID: 35739317 Free PMC article.
Neutrophils migrating towards chemoattractant gradients amplify their recruitment range by releasing the secondary chemoattractant leukotriene B(4) (LTB(4)) refs. (1,2). We previously demonstrated that LTB(4) and its synthesizing enzymes, 5-lipoxygenase (5-LO), 5-LO …
Neutrophils migrating towards chemoattractant gradients amplify their recruitment range by releasing the secondary chemoattractant leukotrie …
Biosynthesis of leukotriene B4.
Wan M, Tang X, Stsiapanava A, Haeggström JZ. Wan M, et al. Semin Immunol. 2017 Oct;33:3-15. doi: 10.1016/j.smim.2017.07.012. Semin Immunol. 2017. PMID: 29042025 Review.
Leukotriene B(4) (LTB(4)) is a lipid mediator derived from arachidonic acid (AA) by the sequential action of 5-lipoxygenase (5-LOX), 5-lipoxygenase-activating protein (FLAP) and LTA(4) hydrolase (LTA(4)H). It was initially recognized for its involvement in the recruitment …
Leukotriene B(4) (LTB(4)) is a lipid mediator derived from arachidonic acid (AA) by the sequential action of 5-lipoxygenase (5-LOX), …
Neutrophilic airways inflammation in lung cancer: the role of exhaled LTB-4 and IL-8.
Carpagnano GE, Palladino GP, Lacedonia D, Koutelou A, Orlando S, Foschino-Barbaro MP. Carpagnano GE, et al. BMC Cancer. 2011 Jun 7;11:226. doi: 10.1186/1471-2407-11-226. BMC Cancer. 2011. PMID: 21649887 Free PMC article.
BACKGROUND: Recent advances in lung cancer biology presuppose its inflammatory origin. In this regard, LTB-4 and IL-8 are recognized to play a crucial role in neutrophil recruitment into airways during lung cancer.Notwithstanding the intriguing hypothesis, th …
BACKGROUND: Recent advances in lung cancer biology presuppose its inflammatory origin. In this regard, LTB-4 and IL-8 are reco …
STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment.
Chelvanambi M, Fecek RJ, Taylor JL, Storkus WJ. Chelvanambi M, et al. J Immunother Cancer. 2021 Feb;9(2):e001906. doi: 10.1136/jitc-2020-001906. J Immunother Cancer. 2021. PMID: 33526609 Free PMC article.
RESULTS: We report that activation of STING within the TME leads to slowed melanoma growth in association with increased production of antiangiogenic factors including Tnfsf15 (Vegi) and Cxcl10, and TLS-inducing factors including Ccl19, Ccl21, Lta, Ltb and Light. Therapeut …
RESULTS: We report that activation of STING within the TME leads to slowed melanoma growth in association with increased production of antia …
273 results