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A pan-cancer analysis of the oncogenic role of leucine zipper protein 2 in human cancer.
Feng D, Shi X, Zhu W, Zhang F, Li D, Han P, Wei Q, Yang L. Feng D, et al. Exp Hematol Oncol. 2022 Sep 15;11(1):55. doi: 10.1186/s40164-022-00313-x. Exp Hematol Oncol. 2022. PMID: 36109820 Free PMC article.
In this study, we aimed to perform a pan-cancer analysis of leucine zipper protein 2 (LUZP2). A standardized TCGA pan-cancer dataset was downloaded. ...In conclusion, the results of our initial pan-cancer investigation provided a somewhat thorough unde …
In this study, we aimed to perform a pan-cancer analysis of leucine zipper protein 2 (LUZP2). A standardized TCGA pan-cance …
Downregulation of LUZP2 Is Correlated with Poor Prognosis of Low-Grade Glioma.
Li Y, Deng G, Qi Y, Zhang H, Jiang H, Geng R, Ye Z, Liu B, Chen Q. Li Y, et al. Biomed Res Int. 2020 Jul 9;2020:9716720. doi: 10.1155/2020/9716720. eCollection 2020. Biomed Res Int. 2020. PMID: 32695826 Free PMC article.
However, the biological behavior of LGG is not very clear at present. This study was aimed at exploring the role of LUZP2 in LGG. METHODS: By data mining in The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA), the expression, clinical characteristi …
However, the biological behavior of LGG is not very clear at present. This study was aimed at exploring the role of LUZP2 in LGG. MET …
Leucine zipper protein 2 serves as a prognostic biomarker for prostate cancer correlating with immune infiltration and epigenetic regulation.
Feng D, Zhu W, Shi X, Wei W, Han P, Wei Q, Yang L. Feng D, et al. Heliyon. 2022 Sep 29;8(10):e10750. doi: 10.1016/j.heliyon.2022.e10750. eCollection 2022 Oct. Heliyon. 2022. PMID: 36217461 Free PMC article.
BACKGROUND: We sought to determine whether leucine zipper protein 2 (LUZP2) could benefit men with prostate cancer (PCa) undergoing radical radiotherapy (RT) or prostatectomy (RP). ...Additionally, tumor purity was positively correlated with LUZP2. We found t …
BACKGROUND: We sought to determine whether leucine zipper protein 2 (LUZP2) could benefit men with prostate cancer (PCa) under …
Deletion of Luzp2 Does Not Cause Hearing Loss in Mice.
Cheng C, Zhu G, Wang K, Bu C, Li S, Qiu Y, Lu J, Ji X, Hao W, Wang J, Zhu C, Yang Y, Gu Y, Qian X, Yu C, Gao X. Cheng C, et al. Neurosci Bull. 2024 Apr 9. doi: 10.1007/s12264-024-01202-5. Online ahead of print. Neurosci Bull. 2024. PMID: 38589712
To determine the importance of Luzp2 in auditory function, we generated mice deficient in Luzp2. ...However, the loss of Luzp2 did not result in any changes in auditory threshold. HCs or synapse number and HC stereocilia morphology in Luzp2 knockout mi …
To determine the importance of Luzp2 in auditory function, we generated mice deficient in Luzp2. ...However, the loss of Lu …
Parkinson's Disease as a Risk Factor for Prostate Adenocarcinoma: A Molecular Point of View.
Liu T, Yang Z, Liu S, Wei J. Liu T, et al. Gerontology. 2023;69(8):986-1001. doi: 10.1159/000530088. Epub 2023 Mar 15. Gerontology. 2023. PMID: 36921580
INTRODUCTION: Cancer and neurodegeneration are two major leading causes of morbidity and death worldwide. Neurodegeneration results in excessive neuronal cell death, and cancer emerges from increased proliferation and resistance to cell death. ...
INTRODUCTION: Cancer and neurodegeneration are two major leading causes of morbidity and death worldwide. Neurodegeneration results i …
Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer.
Zhao J, Zhao Y, Wang L, Zhang J, Karnes RJ, Kohli M, Wang G, Huang H. Zhao J, et al. Oncotarget. 2016 Jun 21;7(25):38551-38565. doi: 10.18632/oncotarget.9535. Oncotarget. 2016. PMID: 27221037 Free PMC article.
Expression of AR-eRNAs and related mRNAs in the loci of FTO, LUZP2, MARC1 and NCAM2 were further verified by real-time RT-PCR. Silencing of LUZP2 inhibited, but silencing of MARC1 increased the growth of enzalutamide-resistant C4-2 cells. ...
Expression of AR-eRNAs and related mRNAs in the loci of FTO, LUZP2, MARC1 and NCAM2 were further verified by real-time RT-PCR. Silenc …
Construction and evaluation of a prognostic risk model of tumor metastasis-related genes in patients with non-small cell lung cancer.
Ding H, Shi L, Chen Z, Lu Y, Tian Z, Xiao H, Deng X, Chen P, Zhang Y. Ding H, et al. BMC Med Genomics. 2022 Sep 2;15(1):187. doi: 10.1186/s12920-022-01341-6. BMC Med Genomics. 2022. PMID: 36056349 Free PMC article.
BACKGROUND: Lung cancer is a high-incidence cancer, and it is also the most common cause of cancer death worldwide. 80-85% of lung cancer cases can be classified as non-small cell lung cancer (NSCLC). ...GO functions and KEGG pathways analysis r …
BACKGROUND: Lung cancer is a high-incidence cancer, and it is also the most common cause of cancer death worldwide. 80- …
Identification of senescence-related molecular subtypes and key genes for prostate cancer.
Feng DC, Zhu WZ, Shi X, Xiong Q, You J, Wei Q, Yang L. Feng DC, et al. Asian J Androl. 2023 Mar-Apr;25(2):223-229. doi: 10.4103/aja202258. Asian J Androl. 2023. PMID: 36124532 Free PMC article.
We identified distinct senescence-related molecular subtypes and critical genes among prostate cancer (PCa) patients undergoing radical prostatectomy (RP) or radical radiotherapy (RT). ...In terms of the tumor immune environment (TME) analysis, compared with cluster 1, …
We identified distinct senescence-related molecular subtypes and critical genes among prostate cancer (PCa) patients undergoing radic …
Cloning, functional study and comparative mapping of Luzp2 to mouse chromosome 7 and human chromosome 11p13-11p14.
Wu M, Michaud EJ, Johnson DK. Wu M, et al. Mamm Genome. 2003 May;14(5):323-34. doi: 10.1007/s00335-002-2248-6. Mamm Genome. 2003. PMID: 12856284
Luzp2 is normally expressed only in brain and spinal cord. The human homolog of Luzp2 maps to Chr 11p13-11p14 by radiation-hybrid mapping and is deleted in some patients with Wilms tumor-Aniridia-Genitourinary anomalies-mental Retardation (WAGR) syndrome. Disruption …
Luzp2 is normally expressed only in brain and spinal cord. The human homolog of Luzp2 maps to Chr 11p13-11p14 by radiation-hyb …
An in-silico Approach for Recognition of Long non-coding RNA-Associated Competing Endogenous RNA Axes in Prostate Cancer.
Taheri M, Safarzadeh A, Ghafouri-Fard S, Baniahmad A. Taheri M, et al. Urol J. 2024 Feb 28;21(1):57-73. doi: 10.22037/uj.v20i.7650. Urol J. 2024. PMID: 37245085 Free article.
PURPOSE: Prostate cancer is among the most central sources of cancer-related mortalities. ...We also evaluated the related signaling pathways and the significance of these RNAs in prediction of survival of patients with prostate cancer. CONCLUSION: This study …
PURPOSE: Prostate cancer is among the most central sources of cancer-related mortalities. ...We also evaluated the related sig …
11 results