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Early DNA methylation changes in children developing beta cell autoimmunity at a young age.
Starskaia I, Laajala E, Grönroos T, Härkönen T, Junttila S, Kattelus R, Kallionpää H, Laiho A, Suni V, Tillmann V, Lund R, Elo LL, Lähdesmäki H, Knip M, Kalim UU, Lahesmaa R. Starskaia I, et al. Among authors: laajala e. Diabetologia. 2022 May;65(5):844-860. doi: 10.1007/s00125-022-05657-x. Epub 2022 Feb 10. Diabetologia. 2022. PMID: 35142878 Free PMC article.
Innate immune activity is detected prior to seroconversion in children with HLA-conferred type 1 diabetes susceptibility.
Kallionpää H, Elo LL, Laajala E, Mykkänen J, Ricaño-Ponce I, Vaarma M, Laajala TD, Hyöty H, Ilonen J, Veijola R, Simell T, Wijmenga C, Knip M, Lähdesmäki H, Simell O, Lahesmaa R. Kallionpää H, et al. Among authors: laajala e, laajala td. Diabetes. 2014 Jul;63(7):2402-14. doi: 10.2337/db13-1775. Epub 2014 Feb 18. Diabetes. 2014. PMID: 24550192 Free article.
Standard of hygiene and immune adaptation in newborn infants.
Kallionpää H, Laajala E, Öling V, Härkönen T, Tillmann V, Dorshakova NV, Ilonen J, Lähdesmäki H, Knip M, Lahesmaa R; DIABIMMUNE Study Group. Kallionpää H, et al. Among authors: laajala e. Clin Immunol. 2014 Nov;155(1):136-147. doi: 10.1016/j.clim.2014.09.009. Epub 2014 Sep 22. Clin Immunol. 2014. PMID: 25245264 Free article.
Serum proteomes distinguish children developing type 1 diabetes in a cohort with HLA-conferred susceptibility.
Moulder R, Bhosale SD, Erkkilä T, Laajala E, Salmi J, Nguyen EV, Kallionpää H, Mykkänen J, Vähä-Mäkilä M, Hyöty H, Veijola R, Ilonen J, Simell T, Toppari J, Knip M, Goodlett DR, Lähdesmäki H, Simell O, Lahesmaa R. Moulder R, et al. Among authors: laajala e. Diabetes. 2015 Jun;64(6):2265-78. doi: 10.2337/db14-0983. Epub 2015 Jan 23. Diabetes. 2015. PMID: 25616278
Permutation-based significance analysis reduces the type 1 error rate in bisulphite sequencing data analysis of human umbilical cord blood samples.
Laajala E, Halla-Aho V, Grönroos T, Kalim UU, Vähä-Mäkilä M, Nurmio M, Kallionpää H, Lietzén N, Mykkänen J, Rasool O, Toppari J, Orešič M, Knip M, Lund R, Lahesmaa R, Lähdesmäki H. Laajala E, et al. Epigenetics. 2022 Dec;17(12):1608-1627. doi: 10.1080/15592294.2022.2044127. Epub 2022 Mar 4. Epigenetics. 2022. PMID: 35246015 Free PMC article.
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