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The recognition and removal of cellular poly(ADP-ribose) signals.
Barkauskaite E, Jankevicius G, Ladurner AG, Ahel I, Timinszky G. Barkauskaite E, et al. Among authors: ladurner ag. FEBS J. 2013 Aug;280(15):3491-507. doi: 10.1111/febs.12358. Epub 2013 Jun 18. FEBS J. 2013. PMID: 23711178 Free article. Review.
ADP-ribosyltransferases, an update on function and nomenclature.
Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. Lüscher B, et al. FEBS J. 2022 Dec;289(23):7399-7410. doi: 10.1111/febs.16142. Epub 2021 Sep 13. FEBS J. 2022. PMID: 34323016 Free PMC article.
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation.
Jankevicius G, Hassler M, Golia B, Rybin V, Zacharias M, Timinszky G, Ladurner AG. Jankevicius G, et al. Among authors: ladurner ag. Nat Struct Mol Biol. 2013 Apr;20(4):508-14. doi: 10.1038/nsmb.2523. Epub 2013 Mar 10. Nat Struct Mol Biol. 2013. PMID: 23474712 Free PMC article.
Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.
Sharifi R, Morra R, Appel CD, Tallis M, Chioza B, Jankevicius G, Simpson MA, Matic I, Ozkan E, Golia B, Schellenberg MJ, Weston R, Williams JG, Rossi MN, Galehdari H, Krahn J, Wan A, Trembath RC, Crosby AH, Ahel D, Hay R, Ladurner AG, Timinszky G, Williams RS, Ahel I. Sharifi R, et al. Among authors: ladurner ag. EMBO J. 2013 May 2;32(9):1225-37. doi: 10.1038/emboj.2013.51. Epub 2013 Mar 12. EMBO J. 2013. PMID: 23481255 Free PMC article.
The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks.
Ali AAE, Timinszky G, Arribas-Bosacoma R, Kozlowski M, Hassa PO, Hassler M, Ladurner AG, Pearl LH, Oliver AW. Ali AAE, et al. Among authors: ladurner ag. Nat Struct Mol Biol. 2012 Jun 10;19(7):685-692. doi: 10.1038/nsmb.2335. Nat Struct Mol Biol. 2012. PMID: 22683995 Free PMC article.
A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene.
Singh HR, Nardozza AP, Möller IR, Knobloch G, Kistemaker HAV, Hassler M, Harrer N, Blessing C, Eustermann S, Kotthoff C, Huet S, Mueller-Planitz F, Filippov DV, Timinszky G, Rand KD, Ladurner AG. Singh HR, et al. Among authors: ladurner ag. Mol Cell. 2017 Dec 7;68(5):860-871.e7. doi: 10.1016/j.molcel.2017.11.019. Mol Cell. 2017. PMID: 29220653 Free article.
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.
Timinszky G, Till S, Hassa PO, Hothorn M, Kustatscher G, Nijmeijer B, Colombelli J, Altmeyer M, Stelzer EH, Scheffzek K, Hottiger MO, Ladurner AG. Timinszky G, et al. Among authors: ladurner ag. Nat Struct Mol Biol. 2009 Sep;16(9):923-9. doi: 10.1038/nsmb.1664. Epub 2009 Aug 13. Nat Struct Mol Biol. 2009. PMID: 19680243
MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Kozlowski M, Corujo D, Hothorn M, Guberovic I, Mandemaker IK, Blessing C, Sporn J, Gutierrez-Triana A, Smith R, Portmann T, Treier M, Scheffzek K, Huet S, Timinszky G, Buschbeck M, Ladurner AG. Kozlowski M, et al. Among authors: ladurner ag. EMBO Rep. 2018 Oct;19(10):e44445. doi: 10.15252/embr.201744445. Epub 2018 Sep 3. EMBO Rep. 2018. PMID: 30177554 Free PMC article.
99 results