Laethem RM - Search Results

1

A high throughput sphingomyelinase assay.

Hassler DF, Laethem RM, Smith GK. Hassler DF, et al. Among authors: laethem rm. Methods Enzymol. 2000;311:176-84. doi: 10.1016/s0076-6879(00)11079-1. Methods Enzymol. 2000. PMID: 10563323 No abstract available.

2

Increases in neutral, Mg2+-dependent and acidic, Mg2+-independent sphingomyelinase activities precede commitment to apoptosis and are not a consequence of caspase 3-like activity in Molt-4 cells in response to thymidylate synthase inhibition by GW1843.

Laethem RM, Hannun YA, Jayadev S, Sexton CJ, Strum JC, Sundseth R, Smith GK. Laethem RM, et al. Blood. 1998 Jun 1;91(11):4350-60. Blood. 1998. PMID: 9596684 Free article.

3

Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843.

Wolfe LA, Mullin RJ, Laethem R, Blumenkopf TA, Cory M, Miller JF, Keith BR, Humphreys J, Smith GK. Wolfe LA, et al. Bioconjug Chem. 1999 Jan-Feb;10(1):38-48. doi: 10.1021/bc980057z. Bioconjug Chem. 1999. PMID: 9893962

4

Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.

Laethem RM, Blumenkopf TA, Cory M, Elwell L, Moxham CP, Ray PH, Walton LM, Smith GK. Laethem RM, et al. Arch Biochem Biophys. 1996 Aug 1;332(1):8-18. doi: 10.1006/abbi.1996.0310. Arch Biochem Biophys. 1996. PMID: 8806703

5

Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate.

Smith GK, Banks S, Blumenkopf TA, Cory M, Humphreys J, Laethem RM, Miller J, Moxham CP, Mullin R, Ray PH, Walton LM, Wolfe LA 3rd. Smith GK, et al. Among authors: laethem rm. J Biol Chem. 1997 Jun 20;272(25):15804-16. doi: 10.1074/jbc.272.25.15804. J Biol Chem. 1997. PMID: 9188478 Free article.

6

CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.

Tippin TK, Hamilton G, Moore L, Beaudet EJ, Jolley S, Brodie TA, Andrews RC, Becherer JD, McDougald DL, Gaul MD, Hoivik DJ, Mellon-Kusibab K, Lehmann J, Kliewer S, Novick S, Laethem R, Zhao Z, LeCluyse EL. Tippin TK, et al. Drug Metab Dispos. 2003 Jul;31(7):870-7. doi: 10.1124/dmd.31.7.870. Drug Metab Dispos. 2003. PMID: 12814963

7

Cytochrome P450 expression and metabolism in isolated rabbit renal epithelium.

Koop DR, Laethem RM, Goldner AL, Douglas JG. Koop DR, et al. Among authors: laethem rm. Methods Enzymol. 1991;206:364-71. doi: 10.1016/0076-6879(91)06106-d. Methods Enzymol. 1991. PMID: 1784223 No abstract available.

8

Characterization of the interaction of parathyroid hormone with the mitochondrial ATPase.

Laethem R, Zull JE. Laethem R, et al. Arch Biochem Biophys. 1990 Oct;282(1):161-9. doi: 10.1016/0003-9861(90)90100-d. Arch Biochem Biophys. 1990. PMID: 2145804

9

Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.

Faucette SR, Hawke RL, Lecluyse EL, Shord SS, Yan B, Laethem RM, Lindley CM. Faucette SR, et al. Among authors: laethem rm. Drug Metab Dispos. 2000 Oct;28(10):1222-30. Drug Metab Dispos. 2000. PMID: 10997944

10

Purification and properties of a cytochrome P450 arachidonic acid epoxygenase from rabbit renal cortex.

Laethem RM, Laethem CL, Koop DR. Laethem RM, et al. Among authors: laethem cl. J Biol Chem. 1992 Mar 15;267(8):5552-9. J Biol Chem. 1992. PMID: 1544930 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

19 results

Search Page