Lai Q - Search Results

1

Combination Foretinib and Anti-PD-1 Antibody Immunotherapy for Colorectal Carcinoma.

Fu Y, Peng Y, Zhao S, Mou J, Zeng L, Jiang X, Yang C, Huang C, Li Y, Lu Y, Wu M, Yang Y, Kong T, Lai Q, Wu Y, Yao Y, Wang Y, Gou L, Yang J. Fu Y, et al. Among authors: lai q. Front Cell Dev Biol. 2021 Jul 8;9:689727. doi: 10.3389/fcell.2021.689727. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34307367 Free PMC article.

2

Eradication of growth of HER2-positive ovarian cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate in mouse xenograft model.

Yu L, Wang Y, Yao Y, Li W, Lai Q, Li J, Zhou Y, Kang T, Xie Y, Wu Y, Chen X, Yi C, Gou L, Yang J. Yu L, et al. Among authors: lai q. Int J Gynecol Cancer. 2014 Sep;24(7):1158-64. doi: 10.1097/IGC.0000000000000179. Int J Gynecol Cancer. 2014. PMID: 24987913

3

Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.

Wang Y, Zhang H, Gigant B, Yu Y, Wu Y, Chen X, Lai Q, Yang Z, Chen Q, Yang J. Wang Y, et al. Among authors: lai q. FEBS J. 2016 Jan;283(1):102-11. doi: 10.1111/febs.13555. Epub 2015 Nov 4. FEBS J. 2016. PMID: 26462166 Free article.

4

Therapeutic potential of an anti-HER2 single chain antibody-DM1 conjugates for the treatment of HER2-positive cancer.

Zhang H, Wang Y, Wu Y, Jiang X, Tao Y, Yao Y, Peng Y, Chen X, Fu Y, Yu L, Wang R, Lai Q, Lai W, Li W, Kang Y, Yi S, Lu Y, Gou L, Wu M, Yang J. Zhang H, et al. Among authors: lai w, lai q. Signal Transduct Target Ther. 2017 May 19;2:17015. doi: 10.1038/sigtrans.2017.15. eCollection 2017. Signal Transduct Target Ther. 2017. PMID: 29263918 Free PMC article.

5

Promiximab-duocarmycin, a new CD56 antibody-drug conjugates, is highly efficacious in small cell lung cancer xenograft models.

Yu L, Lu Y, Yao Y, Liu Y, Wang Y, Lai Q, Zhang R, Li W, Wang R, Fu Y, Tao Y, Yi S, Gou L, Chen L, Yang J. Yu L, et al. Among authors: lai q. Oncotarget. 2017 Dec 26;9(4):5197-5207. doi: 10.18632/oncotarget.23708. eCollection 2018 Jan 12. Oncotarget. 2017. PMID: 29435172 Free PMC article.

6

Preparation and anti-cancer evaluation of promiximab-MMAE, an anti-CD56 antibody drug conjugate, in small cell lung cancer cell line xenograft models.

Yu L, Yao Y, Wang Y, Zhou S, Lai Q, Lu Y, Liu Y, Zhang R, Wang R, Liu C, Gou L, Chen X, Yu Y, Chen Q, Yang J. Yu L, et al. Among authors: lai q. J Drug Target. 2018 Dec;26(10):905-912. doi: 10.1080/1061186X.2018.1450413. Epub 2018 Apr 13. J Drug Target. 2018. PMID: 29630426

7

A novel 5T4-targeting antibody-drug conjugate H6-DM4 exhibits potent therapeutic efficacy in gastrointestinal tumor xenograft models.

Wang R, Lai Q, Tang L, Tao Y, Yao Y, Liu Y, Lu Y, Shen C, Lu R, Fan C, Zhang R, Wang Y, Yu L, Yang T, Wu Y, Peng Y, Wei X, Fu Y, Lai W, Gou L, Yang J. Wang R, et al. Among authors: lai w, lai q. Am J Cancer Res. 2018 Apr 1;8(4):610-623. eCollection 2018. Am J Cancer Res. 2018. PMID: 29736307 Free PMC article.

8

Expression of 5T4 extracellular domain fusion protein and preparation of anti-5T4 monoclonal antibody with high affinity and internalization efficiency.

Wang R, Lai Q, Lu Y, Zhou Y, Tang L, Tao Y, Yao Y, Yu L, Liu Y, Wang Y, Zhang R, Jiang X, Gou L, Yang J. Wang R, et al. Among authors: lai q. Protein Expr Purif. 2019 Jun;158:51-58. doi: 10.1016/j.pep.2018.07.003. Epub 2018 Jul 6. Protein Expr Purif. 2019. PMID: 29981846

9

Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.

Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J. Lai Q, et al. Among authors: lai w. Eur J Med Chem. 2018 Aug 5;156:162-179. doi: 10.1016/j.ejmech.2018.05.010. Epub 2018 May 10. Eur J Med Chem. 2018. PMID: 30006162

10

Targeting of DDR1 with antibody-drug conjugates has antitumor effects in a mouse model of colon carcinoma.

Tao Y, Wang R, Lai Q, Wu M, Wang Y, Jiang X, Zeng L, Zhou S, Li Z, Yang T, Yao Y, Wu Y, Yu L, Fu Y, Lai W, Peng Y, Lu Y, Zhang Z, Guo C, Zhang G, Gou L, Yang J. Tao Y, et al. Among authors: lai w, lai q. Mol Oncol. 2019 Sep;13(9):1855-1873. doi: 10.1002/1878-0261.12520. Epub 2019 Jul 22. Mol Oncol. 2019. PMID: 31116512 Free PMC article.

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