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GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers.
Rasheed SAK, Leong HS, Lakshmanan M, Raju A, Dadlani D, Chong FT, Shannon NB, Rajarethinam R, Skanthakumar T, Tan EY, Hwang JSG, Lim KH, Tan DS, Ceppi P, Wang M, Tergaonkar V, Casey PJ, Iyer NG. Rasheed SAK, et al. Among authors: lakshmanan m. Oncogene. 2018 Mar;37(10):1340-1353. doi: 10.1038/s41388-017-0038-6. Epub 2017 Dec 19. Oncogene. 2018. PMID: 29255247 Free PMC article.
Platform comparison for evaluation of ALK protein immunohistochemical expression, genomic copy number and hotspot mutation status in neuroblastomas.
Yan B, Kuick CH, Lim M, Venkataraman K, Tennakoon C, Loh E, Lian D, Leong MY, Lakshmanan M, Tergaonkar V, Sung WK, Soh SY, Chang KT. Yan B, et al. Among authors: lakshmanan m. PLoS One. 2014 Sep 4;9(9):e106575. doi: 10.1371/journal.pone.0106575. eCollection 2014. PLoS One. 2014. PMID: 25188507 Free PMC article.
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers.
Kumar R, Coronel L, Somalanka B, Raju A, Aning OA, An O, Ho YS, Chen S, Mak SY, Hor PY, Yang H, Lakshmanan M, Itoh H, Tan SY, Lim YK, Wong APC, Chew SH, Huynh TH, Goh BC, Lim CY, Tergaonkar V, Cheok CF. Kumar R, et al. Among authors: lakshmanan m. Nat Commun. 2018 Sep 26;9(1):3931. doi: 10.1038/s41467-018-05805-1. Nat Commun. 2018. PMID: 30258081 Free PMC article.
Targeting N-myristoylation for therapy of B-cell lymphomas.
Beauchamp E, Yap MC, Iyer A, Perinpanayagam MA, Gamma JM, Vincent KM, Lakshmanan M, Raju A, Tergaonkar V, Tan SY, Lim ST, Dong WF, Postovit LM, Read KD, Gray DW, Wyatt PG, Mackey JR, Berthiaume LG. Beauchamp E, et al. Among authors: lakshmanan m. Nat Commun. 2020 Oct 22;11(1):5348. doi: 10.1038/s41467-020-18998-1. Nat Commun. 2020. PMID: 33093447 Free PMC article.
PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production.
Srinivas US, Tay NSC, Jaynes P, Anbuselvan A, Ramachandran GK, Wardyn JD, Hoppe MM, Hoang PM, Peng Y, Lim S, Lee MY, Peethala PC, An O, Shendre A, Tan BWQ, Jemimah S, Lakshmanan M, Hu L, Jakhar R, Sachaphibulkij K, Lim LHK, Pervaiz S, Crasta K, Yang H, Tan P, Liang C, Ho L, Khanchandani V, Kappei D, Yong WP, Tan DSP, Bordi M, Campello S, Tam WL, Frezza C, Jeyasekharan AD. Srinivas US, et al. Among authors: lakshmanan m. Oncogene. 2022 Mar;41(13):1986-2002. doi: 10.1038/s41388-022-02219-8. Epub 2022 Mar 2. Oncogene. 2022. PMID: 35236967
314 results