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High-potency ligands for DREADD imaging and activation in rodents and monkeys.
Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris PJ, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M. Bonaventura J, et al. Among authors: lam s. Nat Commun. 2019 Oct 11;10(1):4627. doi: 10.1038/s41467-019-12236-z. Nat Commun. 2019. PMID: 31604917 Free PMC article.
Opioid-galanin receptor heteromers mediate the dopaminergic effects of opioids.
Cai NS, Quiroz C, Bonaventura J, Bonifazi A, Cole TO, Purks J, Billing AS, Massey E, Wagner M, Wish ED, Guitart X, Rea W, Lam S, Moreno E, Casadó-Anguera V, Greenblatt AD, Jacobson AE, Rice KC, Casadó V, Newman AH, Winkelman JW, Michaelides M, Weintraub E, Volkow ND, Belcher AM, Ferré S. Cai NS, et al. Among authors: lam s. J Clin Invest. 2019 Mar 26;129(7):2730-2744. doi: 10.1172/JCI126912. J Clin Invest. 2019. PMID: 30913037 Free PMC article.
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability.
Bonaventura J, Lam S, Carlton M, Boehm MA, Gomez JL, Solís O, Sánchez-Soto M, Morris PJ, Fredriksson I, Thomas CJ, Sibley DR, Shaham Y, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: lam s. Mol Psychiatry. 2021 Nov;26(11):6704-6722. doi: 10.1038/s41380-021-01093-2. Epub 2021 Apr 15. Mol Psychiatry. 2021. PMID: 33859356 Free PMC article.
Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior.
Gomez JL, Bonaventura J, Keighron J, Wright KM, Marable DL, Rodriguez LA, Lam S, Carlton ML, Ellis RJ, Jordan CJ, Bi GH, Solis O, Pignatelli M, Bannon MJ, Xi ZX, Tanda G, Michaelides M. Gomez JL, et al. Among authors: lam s. Transl Psychiatry. 2021 Nov 8;11(1):570. doi: 10.1038/s41398-021-01693-0. Transl Psychiatry. 2021. PMID: 34750356 Free PMC article.
Time will tell. Reply to "Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al." by Chen et al.
Bonaventura J, Lam S, Carlton M, Boehm M, Gomez JL, Solís O, Sánchez-Soto M, Morris PJ, Fredriksson I, Thomas CJ, Sibley DR, Shaham Y, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: lam s. Mol Psychiatry. 2022 Apr;27(4):1863-1865. doi: 10.1038/s41380-022-01480-3. Epub 2022 Feb 22. Mol Psychiatry. 2022. PMID: 35194167 Free PMC article. No abstract available.
The show must go on. Reply to "Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al" by Insop Shim.
Bonaventura J, Lam S, Carlton M, Boehm M, Gomez JL, Solís O, Sánchez-Soto M, Morris PJ, Fredriksson I, Thomas CJ, Sibley DR, Shaham Y, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: lam s. Mol Psychiatry. 2023 Dec;28(12):4941-4942. doi: 10.1038/s41380-022-01666-9. Epub 2022 Jun 22. Mol Psychiatry. 2023. PMID: 35732692 No abstract available.
Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search.
Bonaventura J, Gomez JL, Carlton ML, Lam S, Sanchez-Soto M, Morris PJ, Moaddel R, Kang HJ, Zanos P, Gould TD, Thomas CJ, Sibley DR, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: lam s. Mol Psychiatry. 2022 Oct;27(10):4144-4156. doi: 10.1038/s41380-022-01673-w. Epub 2022 Jun 29. Mol Psychiatry. 2022. PMID: 35768639 Free PMC article.
Essential role of P-glycoprotein in the mechanism of action of oliceridine.
Ventriglia E, Rizzo A, Gomez JL, Friedman J, Lam S, Solís O, Rais R, Bonaventura J, Michaelides M. Ventriglia E, et al. Among authors: lam s. Neuropsychopharmacology. 2023 Apr;48(5):831-842. doi: 10.1038/s41386-022-01507-x. Epub 2022 Nov 25. Neuropsychopharmacology. 2023. PMID: 36434081 Free PMC article.
Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging.
Bonaventura J, Boehm MA, Jedema HP, Solis O, Pignatelli M, Song X, Lu H, Richie CT, Zhang S, Gomez JL, Lam S, Morales M, Gharbawie OA, Pomper MG, Stein EA, Bradberry CW, Michaelides M. Bonaventura J, et al. Among authors: lam s. Sci Transl Med. 2023 Jul 26;15(706):eadd1014. doi: 10.1126/scitranslmed.add1014. Epub 2023 Jul 26. Sci Transl Med. 2023. PMID: 37494470 Free PMC article.
4,102 results