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The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2.
Maussang D, Langemeijer E, Fitzsimons CP, Stigter-van Walsum M, Dijkman R, Borg MK, Slinger E, Schreiber A, Michel D, Tensen CP, van Dongen GA, Leurs R, Smit MJ. Maussang D, et al. Among authors: langemeijer e. Cancer Res. 2009 Apr 1;69(7):2861-9. doi: 10.1158/0008-5472.CAN-08-2487. Epub 2009 Mar 24. Cancer Res. 2009. PMID: 19318580 Free article.
Constitutive β-catenin signaling by the viral chemokine receptor US28.
Langemeijer EV, Slinger E, de Munnik S, Schreiber A, Maussang D, Vischer H, Verkaar F, Leurs R, Siderius M, Smit MJ. Langemeijer EV, et al. PLoS One. 2012;7(11):e48935. doi: 10.1371/journal.pone.0048935. Epub 2012 Nov 8. PLoS One. 2012. PMID: 23145028 Free PMC article.
The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties.
van Senten JR, Bebelman MP, Fan TS, Heukers R, Bergkamp ND, van Gasselt P, Langemeijer EV, Slinger E, Lagerweij T, Rahbar A, Stigter-van Walsum M, Maussang D, Leurs R, Musters RJP, van Dongen GAMS, Söderberg-Nauclér C, Würdinger T, Siderius M, Smit MJ. van Senten JR, et al. Among authors: langemeijer ev. J Biol Chem. 2019 Nov 1;294(44):16297-16308. doi: 10.1074/jbc.RA119.007796. Epub 2019 Sep 13. J Biol Chem. 2019. PMID: 31519750 Free PMC article.
Herpesvirus-encoded GPCRs rewire cellular signaling.
Slinger E, Langemeijer E, Siderius M, Vischer HF, Smit MJ. Slinger E, et al. Among authors: langemeijer e. Mol Cell Endocrinol. 2011 Jan 15;331(2):179-84. doi: 10.1016/j.mce.2010.04.007. Epub 2010 Apr 14. Mol Cell Endocrinol. 2011. PMID: 20398729 Review.
Adenoviral vectors expressing siRNAs for discovery and validation of gene function.
Arts GJ, Langemeijer E, Tissingh R, Ma L, Pavliska H, Dokic K, Dooijes R, Mesić E, Clasen R, Michiels F, van der Schueren J, Lambrecht M, Herman S, Brys R, Thys K, Hoffmann M, Tomme P, van Es H. Arts GJ, et al. Among authors: langemeijer e. Genome Res. 2003 Oct;13(10):2325-32. doi: 10.1101/gr.1332603. Epub 2003 Sep 15. Genome Res. 2003. PMID: 12975310 Free PMC article.
Functional selectivity of adenosine A1 receptor ligands?
Langemeijer EV, Verzijl D, Dekker SJ, Ijzerman AP. Langemeijer EV, et al. Purinergic Signal. 2013 Mar;9(1):91-100. doi: 10.1007/s11302-012-9334-3. Epub 2012 Sep 28. Purinergic Signal. 2013. PMID: 23054444 Free PMC article.
Arrayed adenoviral expression libraries for functional screening.
Michiels F, van Es H, van Rompaey L, Merchiers P, Francken B, Pittois K, van der Schueren J, Brys R, Vandersmissen J, Beirinckx F, Herman S, Dokic K, Klaassen H, Narinx E, Hagers A, Laenen W, Piest I, Pavliska H, Rombout Y, Langemeijer E, Ma L, Schipper C, Raeymaeker MD, Schweicher S, Jans M, van Beeck K, Tsang IR, van de Stolpe O, Tomme P, Arts GJ, Donker J. Michiels F, et al. Among authors: langemeijer e. Nat Biotechnol. 2002 Nov;20(11):1154-7. doi: 10.1038/nbt746. Epub 2002 Sep 30. Nat Biotechnol. 2002. PMID: 12355097