Langer R - Search Results

1

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics.

Akinc A, Zumbuehl A, Goldberg M, Leshchiner ES, Busini V, Hossain N, Bacallado SA, Nguyen DN, Fuller J, Alvarez R, Borodovsky A, Borland T, Constien R, de Fougerolles A, Dorkin JR, Narayanannair Jayaprakash K, Jayaraman M, John M, Koteliansky V, Manoharan M, Nechev L, Qin J, Racie T, Raitcheva D, Rajeev KG, Sah DW, Soutschek J, Toudjarska I, Vornlocher HP, Zimmermann TS, Langer R, Anderson DG. Akinc A, et al. Among authors: langer r. Nat Biotechnol. 2008 May;26(5):561-9. doi: 10.1038/nbt1402. Epub 2008 Apr 27. Nat Biotechnol. 2008. PMID: 18438401 Free PMC article.

2

Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo.

Simons M, Edelman ER, DeKeyser JL, Langer R, Rosenberg RD. Simons M, et al. Among authors: langer r. Nature. 1992 Sep 3;359(6390):67-70. doi: 10.1038/359067a0. Nature. 1992. PMID: 1522889

3

Controlled release of a therapeutic protein.

Langer R. Langer R. Nat Med. 1996 Jul;2(7):742-3. doi: 10.1038/nm0796-742. Nat Med. 1996. PMID: 8673913 No abstract available.

4

Drug delivery and targeting.

Langer R. Langer R. Nature. 1998 Apr 30;392(6679 Suppl):5-10. Nature. 1998. PMID: 9579855 Review.

5

Design of imidazole-containing endosomolytic biopolymers for gene delivery.

Pack DW, Putnam D, Langer R. Pack DW, et al. Among authors: langer r. Biotechnol Bioeng. 2000 Jan 20;67(2):217-23. Biotechnol Bioeng. 2000. PMID: 10592519

6

Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library.

Lynn DM, Anderson DG, Putnam D, Langer R. Lynn DM, et al. Among authors: langer r. J Am Chem Soc. 2001 Aug 22;123(33):8155-6. doi: 10.1021/ja016288p. J Am Chem Soc. 2001. PMID: 11506588 No abstract available.

7

A tough biodegradable elastomer.

Wang Y, Ameer GA, Sheppard BJ, Langer R. Wang Y, et al. Among authors: langer r. Nat Biotechnol. 2002 Jun;20(6):602-6. doi: 10.1038/nbt0602-602. Nat Biotechnol. 2002. PMID: 12042865

8

Measuring the pH environment of DNA delivered using nonviral vectors: implications for lysosomal trafficking.

Akinc A, Langer R. Akinc A, et al. Among authors: langer r. Biotechnol Bioeng. 2002 Jun 5;78(5):503-8. doi: 10.1002/bit.20215. Biotechnol Bioeng. 2002. PMID: 12115119

9

Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery.

Akinc A, Lynn DM, Anderson DG, Langer R. Akinc A, et al. Among authors: langer r. J Am Chem Soc. 2003 May 7;125(18):5316-23. doi: 10.1021/ja034429c. J Am Chem Soc. 2003. PMID: 12720443

10

Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.

Anderson DG, Lynn DM, Langer R. Anderson DG, et al. Among authors: langer r. Angew Chem Int Ed Engl. 2003 Jul 14;42(27):3153-8. doi: 10.1002/anie.200351244. Angew Chem Int Ed Engl. 2003. PMID: 12866105 No abstract available.

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