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CD70 defines a subset of proinflammatory and CNS-pathogenic TH1/TH17 lymphocytes and is overexpressed in multiple sclerosis.
Dhaeze T, Tremblay L, Lachance C, Peelen E, Zandee S, Grasmuck C, Bourbonnière L, Larouche S, Ayrignac X, Rébillard RM, Poirier J, Lahav B, Duquette P, Girard M, Moumdjian R, Bouthillier A, Larochelle C, Prat A. Dhaeze T, et al. Among authors: larochelle c. Cell Mol Immunol. 2019 Jul;16(7):652-665. doi: 10.1038/s41423-018-0198-5. Epub 2019 Jan 11. Cell Mol Immunol. 2019. PMID: 30635649 Free PMC article.
DICAM promotes TH17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation.
Charabati M, Grasmuck C, Ghannam S, Bourbonnière L, Fournier AP, Lécuyer MA, Tastet O, Kebir H, Rébillard RM, Hoornaert C, Gowing E, Larouche S, Fortin O, Pittet C, Filali-Mouhim A, Lahav B, Moumdjian R, Bouthillier A, Girard M, Duquette P, Cayrol R, Peelen E, Quintana FJ, Antel JP, Flügel A, Larochelle C, Arbour N, Zandee S, Prat A. Charabati M, et al. Among authors: larochelle c. Sci Transl Med. 2022 Jan 5;14(626):eabj0473. doi: 10.1126/scitranslmed.abj0473. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985970
CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis.
Fournier AP, Zandee S, Charabati M, Peelen E, Tastet O, Alvarez JI, Kebir H, Bourbonnière L, Larouche S, Lahav B, Klement W, Tea F, Bouthillier A, Moumdjian R, Cayrol R, Duquette P, Girard M, Larochelle C, Arbour N, Prat A. Fournier AP, et al. Among authors: larochelle c. Neurol Neuroimmunol Neuroinflamm. 2022 Sep 9;9(6):e200022. doi: 10.1212/NXI.0000000000200022. Print 2022 Nov. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 36241608 Free PMC article.
MCAM+ brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4+ T lymphocytes.
Charabati M, Zandee S, Fournier AP, Tastet O, Thai K, Zaminpeyma R, Lécuyer MA, Bourbonnière L, Larouche S, Klement W, Grasmuck C, Tea F, Zierfuss B, Filali-Mouhim A, Moumdjian R, Bouthillier A, Cayrol R, Peelen E, Arbour N, Larochelle C, Prat A. Charabati M, et al. Among authors: larochelle c. Brain. 2023 Apr 19;146(4):1483-1495. doi: 10.1093/brain/awac389. Brain. 2023. PMID: 36319587 Free PMC article.
ALCAM on human oligodendrocytes mediates CD4 T cell adhesion.
Jamann H, Desu HL, Cui QL, Halaweh A, Tastet O, Klement W, Zandee S, Pernin F, Mamane VH, Ouédraogo O, Daigneault A, Sidibé H, Millette F, Peelen E, Dhaeze T, Hoornaert C, Rébillard RM, Thai K, Grasmuck C, Vande Velde C, Prat A, Arbour N, Stratton JA, Antel J, Larochelle C. Jamann H, et al. Among authors: larochelle c. Brain. 2024 Jan 4;147(1):147-162. doi: 10.1093/brain/awad286. Brain. 2024. PMID: 37640028
93 results