Latz E - Search Results

1

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.

Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, Becker CE, Ediriweera HN, Mullick AE, Golenbock DT, Stuart LM, Latz E, Fitzgerald KA, Moore KJ. Sheedy FJ, et al. Among authors: latz e. Nat Immunol. 2013 Aug;14(8):812-20. doi: 10.1038/ni.2639. Epub 2013 Jun 30. Nat Immunol. 2013. PMID: 23812099 Free PMC article.

2

Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.

Massari P, Henneke P, Ho Y, Latz E, Golenbock DT, Wetzler LM. Massari P, et al. Among authors: latz e. J Immunol. 2002 Feb 15;168(4):1533-7. doi: 10.4049/jimmunol.168.4.1533. J Immunol. 2002. PMID: 11823477

3

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. Fitzgerald KA, et al. Among authors: latz e. Nat Immunol. 2003 May;4(5):491-6. doi: 10.1038/ni921. Nat Immunol. 2003. PMID: 12692549

4

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.

Visintin A, Latz E, Monks BG, Espevik T, Golenbock DT. Visintin A, et al. Among authors: latz e. J Biol Chem. 2003 Nov 28;278(48):48313-20. doi: 10.1074/jbc.M306802200. Epub 2003 Sep 5. J Biol Chem. 2003. PMID: 12960171 Free article.

5

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT. Fitzgerald KA, et al. Among authors: latz e. J Exp Med. 2003 Oct 6;198(7):1043-55. doi: 10.1084/jem.20031023. Epub 2003 Sep 29. J Exp Med. 2003. PMID: 14517278 Free PMC article.

6

Receptor "cross talk" in innate immunity.

Latz E, Golenbock DT. Latz E, et al. J Clin Invest. 2003 Oct;112(8):1136-7. doi: 10.1172/JCI20040. J Clin Invest. 2003. PMID: 14561697 Free PMC article.

7

TLR9 signals after translocating from the ER to CpG DNA in the lysosome.

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. Latz E, et al. Nat Immunol. 2004 Feb;5(2):190-8. doi: 10.1038/ni1028. Epub 2004 Jan 11. Nat Immunol. 2004. PMID: 14716310

8

Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.

Latz E, Franko J, Golenbock DT, Schreiber JR. Latz E, et al. J Immunol. 2004 Feb 15;172(4):2431-8. doi: 10.4049/jimmunol.172.4.2431. J Immunol. 2004. PMID: 14764714

9

Mechanisms of TLR9 activation.

Latz E, Visintin A, Espevik T, Golenbock DT. Latz E, et al. J Endotoxin Res. 2004;10(6):406-12. doi: 10.1179/096805104225006525. J Endotoxin Res. 2004. PMID: 15588423

10

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.

Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM, Fitzgerald KA, Golenbock DT. Schoenemeyer A, et al. Among authors: latz e. J Biol Chem. 2005 Apr 29;280(17):17005-12. doi: 10.1074/jbc.M412584200. Epub 2005 Jan 28. J Biol Chem. 2005. PMID: 15695821 Free article.

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