Lau DKW - Search Results

1

Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.

Currie SL, Lau DKW, Doane JJ, Whitby FG, Okon M, McIntosh LP, Graves BJ. Currie SL, et al. Among authors: lau dkw. Nucleic Acids Res. 2017 Mar 17;45(5):2223-2241. doi: 10.1093/nar/gkx068. Nucleic Acids Res. 2017. PMID: 28161714 Free PMC article.

2

The PNT domain from Drosophila pointed-P2 contains a dynamic N-terminal helix preceded by a disordered phosphoacceptor sequence.

Lau DK, Okon M, McIntosh LP. Lau DK, et al. Protein Sci. 2012 Nov;21(11):1716-25. doi: 10.1002/pro.2151. Epub 2012 Oct 9. Protein Sci. 2012. PMID: 22936607 Free PMC article.

3

ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain.

Currie SL, Doane JJ, Evans KS, Bhachech N, Madison BJ, Lau DKW, McIntosh LP, Skalicky JJ, Clark KA, Graves BJ. Currie SL, et al. Among authors: lau dkw. J Mol Biol. 2017 Oct 13;429(20):2975-2995. doi: 10.1016/j.jmb.2017.06.024. Epub 2017 Jul 17. J Mol Biol. 2017. PMID: 28728983 Free PMC article.

4

Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP.

Nelson ML, Kang HS, Lee GM, Blaszczak AG, Lau DK, McIntosh LP, Graves BJ. Nelson ML, et al. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10026-31. doi: 10.1073/pnas.0915137107. Epub 2010 May 13. Proc Natl Acad Sci U S A. 2010. PMID: 20534573 Free PMC article.

5

Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C.

Escobar-Cabrera E, Lau DK, Giovinazzi S, Ishov AM, McIntosh LP. Escobar-Cabrera E, et al. Structure. 2010 Dec 8;18(12):1642-53. doi: 10.1016/j.str.2010.09.016. Structure. 2010. PMID: 21134643 Free article.

6

Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer.

Butler MS, Roshan-Moniri M, Hsing M, Lau D, Kim A, Yen P, Mroczek M, Nouri M, Lien S, Axerio-Cilies P, Dalal K, Yau C, Ghaidi F, Guo Y, Yamazaki T, Lawn S, Gleave ME, Gregory-Evans CY, McIntosh LP, Cox ME, Rennie PS, Cherkasov A. Butler MS, et al. Oncotarget. 2017 Jun 27;8(26):42438-42454. doi: 10.18632/oncotarget.17124. Oncotarget. 2017. PMID: 28465491 Free PMC article.

7

Characterizing the N- and C-terminal Small ubiquitin-like modifier (SUMO)-interacting motifs of the scaffold protein DAXX.

Escobar-Cabrera E, Okon M, Lau DK, Dart CF, Bonvin AM, McIntosh LP. Escobar-Cabrera E, et al. J Biol Chem. 2011 Jun 3;286(22):19816-29. doi: 10.1074/jbc.M111.231647. Epub 2011 Mar 7. J Biol Chem. 2011. PMID: 21383010 Free PMC article.

8

RPA nucleic acid-binding properties of IFI16-HIN200.

Yan H, Dalal K, Hon BK, Youkharibache P, Lau D, Pio F. Yan H, et al. Biochim Biophys Acta. 2008 Jul-Aug;1784(7-8):1087-97. doi: 10.1016/j.bbapap.2008.04.004. Epub 2008 Apr 22. Biochim Biophys Acta. 2008. PMID: 18472023

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