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A metabolic prosurvival role for PML in breast cancer.
Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, Haigis MC, Maratos-Flier E, Richardson AL, Schafer ZT, Pandolfi PP. Carracedo A, et al. Among authors: laurent g. J Clin Invest. 2012 Sep;122(9):3088-100. doi: 10.1172/JCI62129. Epub 2012 Aug 13. J Clin Invest. 2012. PMID: 22886304 Free PMC article.
Systemic elevation of PTEN induces a tumor-suppressive metabolic state.
Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP. Garcia-Cao I, et al. Among authors: laurent g. Cell. 2012 Mar 30;149(1):49-62. doi: 10.1016/j.cell.2012.02.030. Epub 2012 Mar 6. Cell. 2012. PMID: 22401813 Free PMC article.
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.
German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG Jr, Haigis MC. German NJ, et al. Among authors: laurent g. Mol Cell. 2016 Sep 15;63(6):1006-20. doi: 10.1016/j.molcel.2016.08.014. Mol Cell. 2016. PMID: 27635760 Free PMC article.
Sirtuins regulate key aspects of lipid metabolism.
Lomb DJ, Laurent G, Haigis MC. Lomb DJ, et al. Among authors: laurent g. Biochim Biophys Acta. 2010 Aug;1804(8):1652-7. doi: 10.1016/j.bbapap.2009.11.021. Epub 2009 Dec 2. Biochim Biophys Acta. 2010. PMID: 19962456 Review.
SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism.
Jeong SM, Xiao C, Finley LW, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, Xu X, Li C, Wang RH, Lee J, Csibi A, Cerione R, Blenis J, Clish CB, Kimmelman A, Deng CX, Haigis MC. Jeong SM, et al. Among authors: laurent g. Cancer Cell. 2013 Apr 15;23(4):450-63. doi: 10.1016/j.ccr.2013.02.024. Epub 2013 Apr 4. Cancer Cell. 2013. PMID: 23562301 Free PMC article.
Nuclear respiratory factor 2 induces SIRT3 expression.
Satterstrom FK, Swindell WR, Laurent G, Vyas S, Bulyk ML, Haigis MC. Satterstrom FK, et al. Among authors: laurent g. Aging Cell. 2015 Oct;14(5):818-25. doi: 10.1111/acel.12360. Epub 2015 Jun 24. Aging Cell. 2015. PMID: 26109058 Free PMC article.
Regulation of RAS oncogenicity by acetylation.
Yang MH, Nickerson S, Kim ET, Liot C, Laurent G, Spang R, Philips MR, Shan Y, Shaw DE, Bar-Sagi D, Haigis MC, Haigis KM. Yang MH, et al. Among authors: laurent g. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10843-8. doi: 10.1073/pnas.1201487109. Epub 2012 Jun 18. Proc Natl Acad Sci U S A. 2012. PMID: 22711838 Free PMC article.
1,117 results