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Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss.
He S, Zimmerman MW, Layden HM, Berezovskaya A, Etchin J, Martel MW, Thurston G, Jing CB, van Rooijen E, Kaufman CK, Rodig SJ, Zon LI, Patton EE, Mansour MR, Look AT. He S, et al. Among authors: layden hm. Oncogene. 2021 Sep;40(38):5718-5729. doi: 10.1038/s41388-021-01926-y. Epub 2021 Jul 30. Oncogene. 2021. PMID: 34331013 Free PMC article.
Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zone.
Morrison VE, Houpert MG, Trapani JB, Brockman AA, Kingsley PJ, Katdare KA, Layden HM, Nguena-Jones G, Trevisan AJ, Maguire-Zeiss KA, Marnett LJ, Bix GJ, Ihrie RA, Carter BD. Morrison VE, et al. Among authors: layden hm. bioRxiv [Preprint]. 2023 Mar 6:2023.03.03.531012. doi: 10.1101/2023.03.03.531012. bioRxiv. 2023. PMID: 36945622 Free PMC article. Updated. Preprint.
Human SMARCA5 is continuously required to maintain nucleosome spacing.
Bomber ML, Wang J, Liu Q, Barnett KR, Layden HM, Hodges E, Stengel KR, Hiebert SW. Bomber ML, et al. Among authors: layden hm. Mol Cell. 2023 Feb 16;83(4):507-522.e6. doi: 10.1016/j.molcel.2022.12.018. Epub 2023 Jan 10. Mol Cell. 2023. PMID: 36630954 Free PMC article.