Le CHY - Search Results

1

Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia.

Davids BJ, Liu CM, Hanson EM, Le CHY, Ang J, Hanevik K, Fischer M, Radunovic M, Langeland N, Ferella M, Svärd SG, Ghassemian M, Miyamoto Y, Eckmann L. Davids BJ, et al. Among authors: le chy. Infect Immun. 2019 May 21;87(6):e00219-19. doi: 10.1128/IAI.00219-19. Print 2019 Jun. Infect Immun. 2019. PMID: 30962402 Free PMC article.

2

Giardia Infection of the Small Intestine Induces Chronic Colitis in Genetically Susceptible Hosts.

Dann SM, Le CHY, Hanson EM, Ross MC, Eckmann L. Dann SM, et al. Among authors: le chy. J Immunol. 2018 Jul 15;201(2):548-559. doi: 10.4049/jimmunol.1700824. Epub 2018 Jun 13. J Immunol. 2018. PMID: 29898958 Free PMC article.

3

Conserved metabolic enzymes as vaccine antigens for giardiasis.

Ihara S, Miyamoto Y, Le CHY, Tran VN, Hanson EM, Fischer M, Hanevik K, Eckmann L. Ihara S, et al. Among authors: le chy. PLoS Negl Trop Dis. 2022 Apr 25;16(4):e0010323. doi: 10.1371/journal.pntd.0010323. eCollection 2022 Apr. PLoS Negl Trop Dis. 2022. PMID: 35468132 Free PMC article.

4

IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia.

Dann SM, Manthey CF, Le C, Miyamoto Y, Gima L, Abrahim A, Cao AT, Hanson EM, Kolls JK, Raz E, Cong Y, Eckmann L. Dann SM, et al. Exp Parasitol. 2015 Sep;156:68-78. doi: 10.1016/j.exppara.2015.06.003. Epub 2015 Jun 9. Exp Parasitol. 2015. PMID: 26071205 Free PMC article.

5

Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia.

Kim WJ, Korthals KA, Li S, Le C, Kalisiak J, Sharpless KB, Fokin VV, Miyamoto Y, Eckmann L. Kim WJ, et al. Antimicrob Agents Chemother. 2017 May 24;61(6):e02397-16. doi: 10.1128/AAC.02397-16. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28396548 Free PMC article.

6

Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis.

Lauwaet T, Miyamoto Y, Ihara S, Le C, Kalisiak J, Korthals KA, Ghassemian M, Smith DK, Sharpless KB, Fokin VV, Eckmann L. Lauwaet T, et al. PLoS Negl Trop Dis. 2020 Apr 17;14(4):e0008224. doi: 10.1371/journal.pntd.0008224. eCollection 2020 Apr. PLoS Negl Trop Dis. 2020. PMID: 32302296 Free PMC article.

7

Attenuation of intestinal inflammation in interleukin-10-deficient mice infected with Citrobacter rodentium.

Dann SM, Le C, Choudhury BK, Liu H, Saldarriaga O, Hanson EM, Cong Y, Eckmann L. Dann SM, et al. Infect Immun. 2014 May;82(5):1949-58. doi: 10.1128/IAI.00066-14. Epub 2014 Feb 24. Infect Immun. 2014. PMID: 24566625 Free PMC article.

8

Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera.

Das S, Angsantikul P, Le C, Bao D, Miyamoto Y, Gao W, Zhang L, Eckmann L. Das S, et al. PLoS Negl Trop Dis. 2018 Feb 22;12(2):e0006266. doi: 10.1371/journal.pntd.0006266. eCollection 2018 Feb. PLoS Negl Trop Dis. 2018. PMID: 29470490 Free PMC article.

9

Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo.

Hopper M, Yun JF, Zhou B, Le C, Kehoe K, Le R, Hill R, Jongeward G, Debnath A, Zhang L, Miyamoto Y, Eckmann L, Land KM, Wrischnik LA. Hopper M, et al. Int J Antimicrob Agents. 2016 Dec;48(6):690-694. doi: 10.1016/j.ijantimicag.2016.09.020. Epub 2016 Nov 2. Int J Antimicrob Agents. 2016. PMID: 27839893 Free PMC article.

10

A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target.

He C, Nora GP, Schneider EL, Kerr ID, Hansell E, Hirata K, Gonzalez D, Sajid M, Boyd SE, Hruz P, Cobo ER, Le C, Liu WT, Eckmann L, Dorrestein PC, Houpt ER, Brinen LS, Craik CS, Roush WR, McKerrow J, Reed SL. He C, et al. J Biol Chem. 2010 Jun 11;285(24):18516-27. doi: 10.1074/jbc.M109.086181. Epub 2010 Apr 8. J Biol Chem. 2010. PMID: 20378535 Free PMC article.

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