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Are sirtuins viable targets for improving healthspan and lifespan?
Baur JA, Ungvari Z, Minor RK, Le Couteur DG, de Cabo R. Baur JA, et al. Among authors: le couteur dg. Nat Rev Drug Discov. 2012 Jun 1;11(6):443-61. doi: 10.1038/nrd3738. Nat Rev Drug Discov. 2012. PMID: 22653216 Free PMC article. Review.
Aging biology and novel targets for drug discovery.
Le Couteur DG, McLachlan AJ, Quinn RJ, Simpson SJ, de Cabo R. Le Couteur DG, et al. J Gerontol A Biol Sci Med Sci. 2012 Feb;67(2):168-74. doi: 10.1093/gerona/glr095. Epub 2011 Jun 21. J Gerontol A Biol Sci Med Sci. 2012. PMID: 21693687 Free PMC article. Review.
Resveratrol improves health and survival of mice on a high-calorie diet.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA. Baur JA, et al. Nature. 2006 Nov 16;444(7117):337-42. doi: 10.1038/nature05354. Epub 2006 Nov 1. Nature. 2006. PMID: 17086191 Free PMC article.
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R. Pearson KJ, et al. Cell Metab. 2008 Aug;8(2):157-68. doi: 10.1016/j.cmet.2008.06.011. Epub 2008 Jul 3. Cell Metab. 2008. PMID: 18599363 Free PMC article.
Sex and Aging.
Le Couteur DG, Anderson RM, de Cabo R. Le Couteur DG, et al. J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):139-140. doi: 10.1093/gerona/glx221. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29136099 Free PMC article. No abstract available.
Caloric Restriction Research: New Perspectives on the Biology of Aging.
Anderson RM, Le Couteur DG, de Cabo R. Anderson RM, et al. Among authors: le couteur dg. J Gerontol A Biol Sci Med Sci. 2017 Dec 12;73(1):1-3. doi: 10.1093/gerona/glx212. J Gerontol A Biol Sci Med Sci. 2017. PMID: 29240911 Free PMC article. No abstract available.
The impact of low-protein high-carbohydrate diets on aging and lifespan.
Le Couteur DG, Solon-Biet S, Cogger VC, Mitchell SJ, Senior A, de Cabo R, Raubenheimer D, Simpson SJ. Le Couteur DG, et al. Cell Mol Life Sci. 2016 Mar;73(6):1237-52. doi: 10.1007/s00018-015-2120-y. Epub 2015 Dec 30. Cell Mol Life Sci. 2016. PMID: 26718486 Review.
Aging, drugs, and drug metabolism.
Le Couteur DG, McLachlan AJ, de Cabo R. Le Couteur DG, et al. J Gerontol A Biol Sci Med Sci. 2012 Feb;67(2):137-9. doi: 10.1093/gerona/glr084. Epub 2011 Jul 18. J Gerontol A Biol Sci Med Sci. 2012. PMID: 21768500 No abstract available.
Are glycans the Holy Grail for biomarkers of aging?
Le Couteur DG, Simpson SJ, de Cabo R. Le Couteur DG, et al. J Gerontol A Biol Sci Med Sci. 2014 Jul;69(7):777-8. doi: 10.1093/gerona/glt202. Epub 2013 Dec 10. J Gerontol A Biol Sci Med Sci. 2014. PMID: 24325897
436 results