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Surfactant-free anionic PLA nanoparticles coated with HIV-1 p24 protein induced enhanced cellular and humoral immune responses in various animal models.
Ataman-Onal Y, Munier S, Ganée A, Terrat C, Durand PY, Battail N, Martinon F, Le Grand R, Charles MH, Delair T, Verrier B. Ataman-Onal Y, et al. Among authors: le grand r. J Control Release. 2006 May 15;112(2):175-85. doi: 10.1016/j.jconrel.2006.02.006. Epub 2006 Mar 6. J Control Release. 2006. PMID: 16563545
Improved protection against simian immunodeficiency virus mucosal challenge in macaques primed with a DNA vaccine and boosted with the recombinant modified vaccinia virus Ankara and recombinant Semliki Forest virus.
Martinon F, Brochard P, Ripaux M, Delache B, Aurégan G, Vaslin B, Le Grand R. Martinon F, et al. Among authors: le grand r. Vaccine. 2008 Jan 24;26(4):532-45. doi: 10.1016/j.vaccine.2007.11.025. Epub 2007 Dec 3. Vaccine. 2008. PMID: 18093703
Persistent immune responses induced by a human immunodeficiency virus DNA vaccine delivered in association with electroporation in the skin of nonhuman primates.
Martinon F, Kaldma K, Sikut R, Culina S, Romain G, Tuomela M, Adojaan M, Männik A, Toots U, Kivisild T, Morin J, Brochard P, Delache B, Tripiciano A, Ensoli F, Stanescu I, Le Grand R, Ustav M. Martinon F, et al. Among authors: le grand r. Hum Gene Ther. 2009 Nov;20(11):1291-307. doi: 10.1089/hum.2009.044. Hum Gene Ther. 2009. PMID: 19627235
345 results