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Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients.
Tsoi H, Lam KC, Dong Y, Zhang X, Lee CK, Zhang J, Ng SC, Ng SSM, Zheng S, Chen Y, Fang J, Yu J. Tsoi H, et al. Oncogene. 2017 Nov 2;36(44):6109-6118. doi: 10.1038/onc.2017.86. Epub 2017 Jul 10. Oncogene. 2017. PMID: 28692053 Free PMC article.
Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor.
Ercan D, Zejnullahu K, Yonesaka K, Xiao Y, Capelletti M, Rogers A, Lifshits E, Brown A, Lee C, Christensen JG, Kwiatkowski DJ, Engelman JA, Jänne PA. Ercan D, et al. Oncogene. 2010 Apr 22;29(16):2346-56. doi: 10.1038/onc.2009.526. Epub 2010 Feb 1. Oncogene. 2010. PMID: 20118985 Free PMC article.
Over-expression of ERT(ESX/ESE-1/ELF3), an ets-related transcription factor, induces endogenous TGF-beta type II receptor expression and restores the TGF-beta signaling pathway in Hs578t human breast cancer cells.
Chang J, Lee C, Hahm KB, Yi Y, Choi SG, Kim SJ. Chang J, et al. Oncogene. 2000 Jan 6;19(1):151-4. doi: 10.1038/sj.onc.1203252. Oncogene. 2000. PMID: 10644990
Shared acquired genomic changes in zebrafish and human T-ALL.
Rudner LA, Brown KH, Dobrinski KP, Bradley DF, Garcia MI, Smith AC, Downie JM, Meeker ND, Look AT, Downing JR, Gutierrez A, Mullighan CG, Schiffman JD, Lee C, Trede NS, Frazer JK. Rudner LA, et al. Oncogene. 2011 Oct 13;30(41):4289-96. doi: 10.1038/onc.2011.138. Epub 2011 May 9. Oncogene. 2011. PMID: 21552289 Free PMC article.
Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer.
Chen X, Thakkar H, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK. Chen X, et al. Oncogene. 2001 Sep 20;20(42):6073-83. doi: 10.1038/sj.onc.1204736. Oncogene. 2001. PMID: 11593415
Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element.
Stadler M, Chelbi-Alix MK, Koken MH, Venturini L, Lee C, Saïb A, Quignon F, Pelicano L, Guillemin MC, Schindler C, et al. Stadler M, et al. Oncogene. 1995 Dec 21;11(12):2565-73. Oncogene. 1995. PMID: 8545113
Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation.
Woan KV, Lienlaf M, Perez-Villaroel P, Lee C, Cheng F, Knox T, Woods DM, Barrios K, Powers J, Sahakian E, Wang HW, Canales J, Marante D, Smalley KSM, Bergman J, Seto E, Kozikowski A, Pinilla-Ibarz J, Sarnaik A, Celis E, Weber J, Sotomayor EM, Villagra A. Woan KV, et al. Mol Oncol. 2015 Aug;9(7):1447-1457. doi: 10.1016/j.molonc.2015.04.002. Epub 2015 Apr 24. Mol Oncol. 2015. PMID: 25957812 Free PMC article.
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