Lee M - Search Results

1

Synthesis, DNA binding, cytotoxicity and sequence specificity of a series of imidazole-containing analogs of the benzoic acid mustard distamycin derivative tallimustine containing an alkylating group at the C-terminus.

Brooks N, Lee M, Wright SR, Woo S, Centioni S, Hartley JA. Brooks N, et al. Among authors: lee m. Anticancer Drug Des. 1997 Oct;12(7):591-606. Anticancer Drug Des. 1997. PMID: 9365504

2

Sequence specificity of alkylation for a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size: evidence for increased cytotoxicity with enhanced sequence specificity.

Wyatt MD, Lee M, Garbiras BJ, Souhami RL, Hartley JA. Wyatt MD, et al. Among authors: lee m. Biochemistry. 1995 Oct 10;34(40):13034-41. doi: 10.1021/bi00040a014. Biochemistry. 1995. PMID: 7548062

3

Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin.

Wyatt MD, Garbiras BJ, Haskell MK, Lee M, Souhami RL, Hartley JA. Wyatt MD, et al. Among authors: lee m. Anticancer Drug Des. 1994 Dec;9(6):511-25. Anticancer Drug Des. 1994. PMID: 7880376

4

Molecular and cellular pharmacology of novel photoactive psoralen and coumarin conjugates of pyrrole- and imidazole-containing analogues of netropsin.

Hartley JA, McAdam SR, Das S, Roldan MC, Haskell MK, Lee M. Hartley JA, et al. Among authors: lee m. Anticancer Drug Des. 1994 Jun;9(3):181-97. Anticancer Drug Des. 1994. PMID: 8031451

5

Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents.

Lee M, Rhodes AL, Wyatt MD, Forrow S, Hartley JA. Lee M, et al. Anticancer Drug Des. 1993 Jun;8(3):173-92. Anticancer Drug Des. 1993. PMID: 8517912

6

Design, synthesis and biological evaluation of benzoic acid mustard derivatives of imidazole-containing and C-terminal carboxamide analogues of distamycin.

Hartley JA, Preti CS, Wyatt MD, Lee M. Hartley JA, et al. Among authors: lee m. Drug Des Discov. 1995 Apr;12(4):323-35. Drug Des Discov. 1995. PMID: 9040992

7

Alkylation specificity for a series of distamycin analogues that tether chlorambucil.

Wyatt MD, Lee M, Hartley JA. Wyatt MD, et al. Among authors: lee m. Anticancer Drug Des. 1997 Jan;12(1):49-60. Anticancer Drug Des. 1997. PMID: 9051113

8

The sequence specificity of alkylation for a series of benzoic acid mustard and imidazole-containing distamycin analogues: the importance of local sequence conformation.

Wyatt MD, Lee M, Hartley JA. Wyatt MD, et al. Among authors: lee m. Nucleic Acids Res. 1997 Jun 15;25(12):2359-64. doi: 10.1093/nar/25.12.2359. Nucleic Acids Res. 1997. PMID: 9171086 Free PMC article.

9

Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: synthesis, DNA binding and cytotoxicity studies.

Brooks N, Hartley JA, Simpson JE Jr, Wright SR, Woo S, Centioni S, Fontaine MD, McIntyre TE, Lee M. Brooks N, et al. Among authors: lee m. Bioorg Med Chem. 1997 Aug;5(8):1497-507. doi: 10.1016/s0968-0896(97)00096-5. Bioorg Med Chem. 1997. PMID: 9313856

10

The role of base excision repair in the repair of DNA adducts formed by a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size.

Brooks N, McHugh PJ, Lee M, Hartley JA. Brooks N, et al. Among authors: lee m. Anticancer Drug Des. 1999 Feb;14(1):11-8. Anticancer Drug Des. 1999. PMID: 10363024

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