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Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.
Stinear TP, Mve-Obiang A, Small PL, Frigui W, Pryor MJ, Brosch R, Jenkin GA, Johnson PD, Davies JK, Lee RE, Adusumilli S, Garnier T, Haydock SF, Leadlay PF, Cole ST. Stinear TP, et al. Among authors: lee re. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1345-9. doi: 10.1073/pnas.0305877101. Epub 2004 Jan 21. Proc Natl Acad Sci U S A. 2004. PMID: 14736915 Free PMC article.
A newly discovered mycobacterial pathogen isolated from laboratory colonies of Xenopus species with lethal infections produces a novel form of mycolactone, the Mycobacterium ulcerans macrolide toxin.
Mve-Obiang A, Lee RE, Umstot ES, Trott KA, Grammer TC, Parker JM, Ranger BS, Grainger R, Mahrous EA, Small PL. Mve-Obiang A, et al. Among authors: lee re. Infect Immun. 2005 Jun;73(6):3307-12. doi: 10.1128/IAI.73.6.3307-3312.2005. Infect Immun. 2005. PMID: 15908356 Free PMC article.
Detection of Mycolactone A/B in Mycobacterium ulcerans-Infected Human Tissue.
Sarfo FS, Phillips RO, Rangers B, Mahrous EA, Lee RE, Tarelli E, Asiedu KB, Small PL, Wansbrough-Jones MH. Sarfo FS, et al. Among authors: lee re. PLoS Negl Trop Dis. 2010 Jan 5;4(1):e577. doi: 10.1371/journal.pntd.0000577. PLoS Negl Trop Dis. 2010. PMID: 20052267 Free PMC article.
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Phelps GA, Cheramie MN, Fernando DM, Selchow P, Meyer CJ, Waidyarachchi SL, Dharuman S, Liu J, Meuli M, Molin MD, Killam BY, Murphy PA, Reeve SM, Wilt LA, Anderson SM, Yang L, Lee RB, Temrikar ZH, Lukka PB, Meibohm B, Polikanov YS, Hobbie SN, Böttger EC, Sander P, Lee RE. Phelps GA, et al. Among authors: lee re. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2314101120. doi: 10.1073/pnas.2314101120. Epub 2024 Jan 2. Proc Natl Acad Sci U S A. 2024. PMID: 38165935 Free PMC article.
888 results