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Stable G-quadruplex DNA structures promote replication-dependent genome instability.
Rider SD Jr, Gadgil RY, Hitch DC, Damewood FJ 4th, Zavada N, Shanahan M, Alhawach V, Shrestha R, Shin-Ya K, Leffak M. Rider SD Jr, et al. Among authors: leffak m. J Biol Chem. 2022 Jun;298(6):101947. doi: 10.1016/j.jbc.2022.101947. Epub 2022 Apr 18. J Biol Chem. 2022. PMID: 35447109 Free PMC article.
Replication stalling and DNA microsatellite instability.
Gadgil R, Barthelemy J, Lewis T, Leffak M. Gadgil R, et al. Among authors: leffak m. Biophys Chem. 2017 Jun;225:38-48. doi: 10.1016/j.bpc.2016.11.007. Epub 2016 Nov 22. Biophys Chem. 2017. PMID: 27914716 Free PMC article. Review.
Deficiency of the Fanconi anemia E2 ubiqitin conjugase UBE2T only partially abrogates Alu-mediated recombination in a new model of homology dependent recombination.
Lewis TW, Barthelemy JR, Virts EL, Kennedy FM, Gadgil RY, Wiek C, Linka RM, Zhang F, Andreassen PR, Hanenberg H, Leffak M. Lewis TW, et al. Among authors: leffak m. Nucleic Acids Res. 2019 Apr 23;47(7):3503-3520. doi: 10.1093/nar/gkz026. Nucleic Acids Res. 2019. PMID: 30715513 Free PMC article.
62 results